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United States

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Art. -Nr.: HY-176275

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GSNOR-IN-2

GSNOR-IN-2 (Compound 45) is a S-nitrosoglutathione reductase (GSNOR) inhibitor with an IC₅₀ of 44.12 nM. GSNOR-IN-2 has neuroprotective activity, promising for ischemic stroke research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₇H₂₂N₄O₄
Molecular Weight:466.49

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

GSNOR-IN-2 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

GSNOR-IN-2 (Compound 45) is a S-nitrosoglutathione reductase (GSNOR) inhibitor with an IC₅₀ of 44.12 nM. GSNOR-IN-2 has neuroprotective activity, promising for ischemic stroke research^[1].

IC₅₀ & Target

44.12 nM

Chemical Information

Molecular Weight 466.49
Formel C₂₇H₂₂N₄O₄
SMILES

O=C(O)C(C=C1)=CC(N2C3=CC(OCC)=C(C(N)=O)C=C3)=C1C=C2C(C=C4)=CC=C4N5C=CN=C5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Liang Z, et al. Design, Synthesis, and Anti-ischemic Stroke Activity Evaluation of Novel GSNOR Inhibitors. J Med Chem. 2025 Jun 26;68(12):12969-12990. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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