993 Results for "

15N

" in MedChemExpress (MCE) Product Catalog:
Products (993)

993 Results for "15N" in MCE Product Catalog:

4
L-Glutamine-15N-1
L-Glutamine-15N-1
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4 Cited Publications
Art. -Nr.: HY-N0390S9
CAS. Nr.: 59681-32-2
Synonyms: L-Glutamic acid 5-amide-15N-1
L-Glutamine- 15N-1 is the 15N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na +-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .
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3
L-Glutamine-15N
L-Glutamine-15N
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3 Cited Publications
Art. -Nr.: HY-N0390S
CAS. Nr.: 80143-57-3
Synonyms: L-Glutamic acid 5-amide-15N
L-Glutamine- 15N is the 15N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na +-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .
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2
L-Cysteine-13C3,15N
L-Cysteine-13C3,15N
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2 Cited Publications
Art. -Nr.: HY-Y0337S
CAS. Nr.: 202406-97-1
L-Cysteine- 13C3, 15N is the 13C- and 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .
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2
Hypoxanthine-15N4
Hypoxanthine-15N4
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2 Cited Publications
Art. -Nr.: HY-N0091S7
CAS. Nr.: 77910-30-6
Synonyms: Purin-6-ol-15N4; Sarcine-15N4
Hypoxanthine- 15N4 is the 15N labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .
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2
Glutathione oxidized-13C4,15N2
Glutathione oxidized-13C4,15N2
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2 Cited Publications
Art. -Nr.: HY-D0844S
CAS. Nr.: 1416898-83-3
Synonyms: L-Glutathione oxidized-13C4,15N2; GSSG-13C4,15N2; Oxiglutatione-13C4,15N2
Glutathione oxidized- 13C4, 15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .
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1
L-Isoleucine-15N
L-Isoleucine-15N
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1 Cited Publications
Art. -Nr.: HY-N0771S2
CAS. Nr.: 59935-30-7
L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid .
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1
L-Leucine-13C6,15N
L-Leucine-13C6,15N
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1 Cited Publications
Art. -Nr.: HY-N0486S8
CAS. Nr.: 202406-52-8
L-Leucine- 13C6, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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1
L-Cysteine-15N
L-Cysteine-15N
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1 Cited Publications
Art. -Nr.: HY-Y0337S1
CAS. Nr.: 204523-09-1
L-Cysteine- 15N is the 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .
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1
L-Arginine-15N2 hydrochloride
L-Arginine-15N2 hydrochloride
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1 Cited Publications
Art. -Nr.: HY-N0455AS
CAS. Nr.: 204633-92-1
Synonyms: (S)-(+)-Arginine-15N2 hydrochloride
L-Arginine- 15N2 (hydrochloride) is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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1
Upadacitinib-15N,d2
Upadacitinib-15N,d2
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1 Cited Publications
Art. -Nr.: HY-W727879
Synonyms: ABT-494-15N,d2
Upadacitinib- 15N,d2 (ABT-494- 15N,d2) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- 15N,d2 (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib- 15N,d2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- 15N,d2 (ABT-494) can be used for several autoimmune disorders research .
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1
L-Valine-15N
L-Valine-15N
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1 Cited Publications
Art. -Nr.: HY-N0717S
CAS. Nr.: 59935-29-4
Synonyms: (S)-Valine-15N
L-Valine- 15N ((S)-Valine- 15N) is the 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
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1
Metronidazole-13C2,15N2
Metronidazole-13C2,15N2
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1 Cited Publications
Art. -Nr.: HY-B0318S
CAS. Nr.: 1173020-03-5
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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1
L-Argininosuccinic acid-13C6,15N4 barium, dihydrate
L-Argininosuccinic acid-13C6,15N4 barium, dihydrate
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1 Cited Publications
Art. -Nr.: HY-143876S
CAS. Nr.: 2483829-90-7
L-Argininosuccinic acid- 13C6, 15N4 (barium, dihydrate) is a 15N-labeled and 13C-labled labeled L-Argininosuccinic acid (barium, dihydrate) .
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1
Adenosine monophosphate-13C10,15N5 dilithium
Adenosine monophosphate-13C10,15N5 dilithium
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1 Cited Publications
Art. -Nr.: HY-A0181S
Synonyms: AMP-13C10,15N5 dilithium
Adenosine monophosphate- 13C10, 15N5(AMP- 13C10, 15N5) is the 13C-labeled and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
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1
Uric acid-15N2
Uric acid-15N2
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1 Cited Publications
Art. -Nr.: HY-B2130S1
CAS. Nr.: 62948-75-8
Target:  

Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species (ROS)

Uric acid- 15N2 is the 15N-labeled Uric acid (HY-B2130). Uric acid is an orally active oxygen free radical scavenger that helps maintain stable blood pressure and combat oxidative stress. Uric acid can scavenge ROS, such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation. Uric acid can be used as a modeling agent in research on hyperuricemia-induced hypertension models .
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1
L-Asparagine-15N2 monohydrate
L-Asparagine-15N2 monohydrate
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1 Cited Publications
Art. -Nr.: HY-N0667S2
CAS. Nr.: 287484-32-6
Synonyms: (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate
L-Asparagine- 15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
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1
Hypoxanthine-13C5,15N4
Hypoxanthine-13C5,15N4
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1 Cited Publications
Art. -Nr.: HY-N0091S
CAS. Nr.: 1987883-25-9
Synonyms: Purin-6-ol-13C5,15N4; Sarcine-13C5,15N4
Hypoxanthine- 13C5, 15N4 is a 15N-labeled and 13C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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1
L-Glutamine-15N2
L-Glutamine-15N2
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1 Cited Publications
Art. -Nr.: HY-N0390S8
CAS. Nr.: 204451-48-9
Synonyms: L-Glutamic acid 5-amide-15N2
L-Glutamine- 15N2 is the 15N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na +-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .
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1
ATP-15N5 dilithium
ATP-15N5 dilithium
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1 Cited Publications
Art. -Nr.: HY-B2176S5
Synonyms: Adenosine 5'-triphosphate-15N5 dilithium
ATP- 15N5 (Adenosine 5'-triphosphate-ATP- 15N5) dilithium is the 15N5-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice .
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1
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
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1 Cited Publications
Art. -Nr.: HY-N7702
CAS. Nr.: 883715-23-9
Category:  

Natural Products other families Metabolic Disease Plants Disease Research Fields

Target:  

Wnt β-catenin

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide is a macamide isolated from Maca (Lepidium meyenii Walp.) N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and consequent bone formation through activating the canonical Wnt/β‐catenin signaling pathway. N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide can be used for the research of osteoporosis .
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