sEH-IN-26
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases.
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- CAS. Nr.: 2222-58-4
- Formel: C14H26N2O
- Molecular Weight:238.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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sEH |
sEH-IN-26 (compound 57) potently inhibits soluble epoxide hydrolase, with an IC50 of 0.06 μM against mouse sEH and 0.16 μM against human sEH. It shows almost no inhibitory effect on rat microsomal mEH, with an IC50 greater than 500 μM, and exhibits extremely high subtype selectivity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2222-58-4
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Molecular Weight 238.37
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Formel C14H26N2O
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SMILES
O=C(NC1CCCCC1)NCC2CCCCC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)