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Art. -Nr.: HY-149895

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Syk-IN-7

Syk-IN-7 (compound 17) is an inhibitor of spleen tyrosine kinase (SYK).

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CAS. Nr.: 3050715-41-5
Formel: C₂₆H₃₁N₉O₄
Molecular Weight:533.58

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Syk-IN-7 Chemical Structure

CAS. Nr.: 3050715-41-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Syk-IN-7 (compound 17) is an inhibitor of spleen tyrosine kinase (SYK)^[1].

IC₅₀ & Target

Syk^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
SUD4	IC₅₀	0.99 μM Compound: 17	Cytotoxicity against human SU-DHL-4 cells assessed as reduction in cell viability Cytotoxicity against human SU-DHL-4 cells assessed as reduction in cell viability	[PMID: 37270074]

Chemical Information

CAS. Nr. 3050715-41-5
Molecular Weight 533.58
Formel C₂₆H₃₁N₉O₄
SMILES

CC1=NN(C=C1CN(C)CCOCCNC2=O)C3=CC=NC(NC4=CC=C(N(CCOC(C)=O)N=C52)C5=C4)=N3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Grimster NP, et al. Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors. Bioorg Med Chem Lett. 2023 Jul 15;91:129352. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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