Igfbp1 - insulin-like growth factor binding protein 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16006

Summary

Enables insulin-like growth factor binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Located in extracellular space. Is expressed in several structures, including blastocyst; early embryo; liver; and secondary oocyte. Human ortholog(s) of this gene implicated in diabetic angiopathy. Orthologous to human IGFBP1 (Insulin like growth factor binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp1 Products (1)

mRNA Protein Name
NM_008341.4 NP_032367.3 insulin-like growth factor-binding protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables insulin-like growth factor binding IPI
IPI: Inferred from physical interaction
7679139 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to insulin IDA
IDA: Inferred from direct assay
29867121 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
7510770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 1

  • IBP-1

  • IGF-binding protein 1

  • INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1)

Recombinant Igfbp1 Proteins

Cat. No. Product Name Accession Purity
HY-P700256 IGFBP-1 Protein, Mouse (SUMO, His) P47876 (A26-N272) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06624 IGFBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174652 Human IGFBP1 mRNA / Unkown
HY-RS17236 Igfbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23689 Igfbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igfbp1 NCBI NCBI:3484