Fluoroclebopride
Based on 1 Customer Validation
Fluoroclebopride binds reversibly to dopamine receptors. 18F labeled fluoroclebopride has been used as a probe for studying D2/D3 receptor availability via PET in various monkey models.
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- Pureté: 99.90%
- CAS No.: 154540-49-5
- Formule: C20H23ClFN3O2
- Masse moléculaire:391.87
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Chemical Information
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CAS No. 154540-49-5
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Appearance Solid
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Masse moléculaire 391.87
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Formule C20H23ClFN3O2
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Color White to off-white
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SMILES
O=C(NC1CCN(CC2=CC=C(F)C=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : ≥ 125 mg/mL (318.98 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Nader MA, Czoty PW. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry. 2005 Aug;162(8):1473-82. [Content Brief]
[2]. Czoty PW, et al. Effects of repeated treatment with the dopamine D2/D3 receptor partial agonist aripiprazole on striatal D2/D3 receptor availability in monkeys. Psychopharmacology (Berl). 2013 Sep 29:10.1007/s00213-013-3274-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5519 mL | 12.7593 mL | 25.5187 mL | 63.7967 mL |
| 5 mM | 0.5104 mL | 2.5519 mL | 5.1037 mL | 12.7593 mL | |
| 10 mM | 0.2552 mL | 1.2759 mL | 2.5519 mL | 6.3797 mL | |
| 15 mM | 0.1701 mL | 0.8506 mL | 1.7012 mL | 4.2531 mL | |
| 20 mM | 0.1276 mL | 0.6380 mL | 1.2759 mL | 3.1898 mL | |
| 25 mM | 0.1021 mL | 0.5104 mL | 1.0207 mL | 2.5519 mL | |
| 30 mM | 0.0851 mL | 0.4253 mL | 0.8506 mL | 2.1266 mL | |
| 40 mM | 0.0638 mL | 0.3190 mL | 0.6380 mL | 1.5949 mL | |
| 50 mM | 0.0510 mL | 0.2552 mL | 0.5104 mL | 1.2759 mL | |
| 60 mM | 0.0425 mL | 0.2127 mL | 0.4253 mL | 1.0633 mL | |
| 80 mM | 0.0319 mL | 0.1595 mL | 0.3190 mL | 0.7975 mL | |
| 100 mM | 0.0255 mL | 0.1276 mL | 0.2552 mL | 0.6380 mL |
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