Hyou1 - hypoxia up-regulated 1 Gene

Also Known as Cab140; Orp150

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192235

Summary

Predicted to enable ATP binding activity and chaperone binding activity. Involved in negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway and response to hypoxia. Located in smooth endoplasmic reticulum. Human ortholog(s) of this gene implicated in immunodeficiency 59. Orthologous to human HYOU1 (hypoxia up-regulated 1). [provided by Alliance of Genome Resources, Apr 2022]

Hyou1 Products (2)

mRNA Protein Name
NM_001034028.1 NP_001029200.1 hypoxia up-regulated protein 1 precursor
NM_138867.2 NP_620222.2 hypoxia up-regulated protein 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
11231630 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
8617779 RGD
Cellular Component GO Annotation Evidence Références Source
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
22665516 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hypoxia up-regulated protein 1

  • 150 kDa oxygen-regulated protein

  • ORP-150

  • oxygen regulated protein (150kD)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-162334 HYOU1-IN-1 Inhibitor 98.32% Unkown
HY-RS06503 HYOU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19443 Hyou1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25935 Hyou1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hyou1 NCBI NCBI:10525