PLEKHO2 - pleckstrin homology domain containing O2 Gene

Also Known as PP1628; pp9099; PLEKHQ1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80301

About PLEKHO2

This gene has 2 transcripts (splice variants), 198 orthologues and 1 paralogue. Broad expression in spleen (RPKM 55.3), bone marrow (RPKM 20.9) and 23 other tissues.

Summary

Predicted to act upstream of or within macrophage apoptotic process. Predicted to be located in extracellular region and ficolin-1-rich granule lumen. [provided by Alliance of Genome Resources, Apr 2022]

PLEKHO2 Products (2)

mRNA Protein Name
NM_001195059.2 NP_001181988.1 pleckstrin homology domain-containing family O member 2 isoform 2
NM_025201.5 NP_079477.2 pleckstrin homology domain-containing family O member 2 isoform 1
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLEKHO2 Protein Structure

PH

PH: PH domain (20 - 117)

  • 0
  • 100
  • 200
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  • 400
  • 490 a.a.
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family O member 2

  • PH domain-containing family O member 2

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PLEKHO2 RGD RGD:1305718
Mus musculus PLEKHO2 MGD MGI:2143132
Canis familiaris PLEKHO2 VGNC VGNC:59125
Others PLEKHO2 NCBI