PLEKHO2 - pleckstrin homology domain containing O2 Gene
Also Known as PP1628; pp9099; PLEKHQ1
Species: Homo sapiens
About PLEKHO2
This gene has 2 transcripts (splice variants), 198 orthologues and 1 paralogue. Broad expression in spleen (RPKM 55.3), bone marrow (RPKM 20.9) and 23 other tissues.
Summary
Predicted to act upstream of or within macrophage apoptotic process. Predicted to be located in extracellular region and ficolin-1-rich granule lumen. [provided by Alliance of Genome Resources, Apr 2022]
PLEKHO2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001195059.2 | NP_001181988.1 | pleckstrin homology domain-containing family O member 2 isoform 2 |
| NM_025201.5 | NP_079477.2 | pleckstrin homology domain-containing family O member 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
PLEKHO2 Protein Structure
PH: PH domain (20 - 117)
- 0
- 100
- 200
- 300
- 400
- 490 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
pleckstrin homology domain-containing family O member 2 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | PLEKHO2 | RGD | RGD:1305718 |
| Mus musculus | PLEKHO2 | MGD | MGI:2143132 |
| Canis familiaris | PLEKHO2 | VGNC | VGNC:59125 |
| Others | PLEKHO2 | NCBI |