Twist1 - twist family bHLH transcription factor 1 Gene

Also Known as Twist

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85489

Summary

Predicted to enable several functions, including E-box binding activity; bHLH transcription factor binding activity; and protein homodimerization activity. Involved in several processes, including odontogenesis; positive regulation of epithelial cell proliferation; and roof of mouth development. Located in nucleus. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in Saethre-Chotzen syndrome; Sweeney-Cox syndrome; acrocephalosyndactylia; and craniosynostosis. Orthologous to human TWIST1 (twist family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Twist1 Products (1)

mRNA Protein Name
NM_053530.2 NP_445982.1 twist-related protein 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
involved in bone development IEP
IEP: Inferred from expression pattern
8773900 RGD
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
19893041 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
10485844 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19893041 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
19276370 RGD
involved in roof of mouth development IEP
IEP: Inferred from expression pattern
11330859 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

twist-related protein 1

  • twist basic helix-loop-helix transcription factor 1

  • twist gene homolog 1

  • twist homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-N2013 Aristolactam I 99.44% Unkown
HY-RS15281 TWIST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179340 Antiproliferative agent-74 Inducer / Unkown
HY-179452 KRAS G13D-IN-2 Inhibitor / Unkown
HY-182069 CDK9-IN-47 / Unkown
HY-RS20201 Twist1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26705 Twist1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Twist1 NCBI NCBI:7291