1. Apoptosis
  2. Caspase
  3. Aristolactam I

Aristolactam I (Synonyms: Aristololactam; Aristolactam)

Cat. No.: HY-N2013
Handling Instructions

Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway.

For research use only. We do not sell to patients.

Aristolactam I Chemical Structure

Aristolactam I Chemical Structure

CAS No. : 13395-02-3

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Description

Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway[1].

Molecular Weight

293.27

Formula

C₁₇H₁₁NO₄

CAS No.

13395-02-3

SMILES

O=C1NC2=C(C3=C4C(C(OC)=CC=C4)=C2)C1=CC5=C3OCO5

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Aristolactam I
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