GCNA - germ cell nuclear acidic peptidase Gene

Also Known as ACRC; NAAR1; SPGFX4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 93953

About GCNA

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:71,578,437-71,613,583 (from NCBI)

This gene has 3 transcripts (splice variants) and 129 orthologues. Biased expression in testis (RPKM 6.8), adrenal (RPKM 2.2) and 12 other tissues.

Summary

Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

GCNA Products (1)

mRNA Protein Name
NM_052957.5 NP_443189.1 germ cell nuclear acidic protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables SUMO polymer binding IDA
IDA: Inferred from direct assay
30914427 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
30914427 GOA
Biological Process GO Annotation Evidence Références Source
involved in protein-DNA covalent cross-linking repair IMP
IMP: Inferred from mutant phenotype
30914427 GOA
Cellular Component GO Annotation Evidence Références Source
located in PML body IDA
IDA: Inferred from direct assay
30914427 GOA
located in nucleus IDA
IDA: Inferred from direct assay
27718356 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GCNA Protein Structure

SprT-like

SprT-like: SprT-like family (522 - 677)

  • 0
  • 200
  • 400
  • 600
  • 691 a.a.
Protein Preferred Names Protein Names

germ cell nuclear acidic protein

  • acidic repeat containing

Related Diseases

Diseases Alias
Spermatogenic Failure, X-Linked, 4

  • SPGFX4
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Ruijs-Aalfs Syndrome

  • Progeroid Features-Hepatocellular Carcinoma Predisposition Syndrome

  • RJALS
Kenny-Caffey Syndrome, Type 2

  • KCS2

  • Kenny-Caffey Syndrome Type 2

  • Autosomal Dominant Kenny-Caffey Syndrome

  • Kenny Syndrome

  • Dwarfism, Cortical Thickening Of Tubular Bones, And Transient Hypocalcemia

  • Dwarfism, Cortical Thickening Of Tubular Bones And Transient Hypocalcemia

  • Kenny-Caffey Syndrome, Autosomal Dominant

  • Kenny-Caffey Syndrome 2

  • Dwarfism With Cortical Thickening Of Tubular Bones And Transient Hypocalcemia

  • Kenny-Caffey Syndrome
Childhood Germ Cell Cancer

  • Pediatric Germ Cell Tumor

  • Paediatric Germ Cell Cancer

  • Paediatric Germ Cell Neoplasm

  • Pediatric Germ Cell Cancer

  • Pediatric Germ Cell Neoplasm
Corneal Staphyloma

  • Staphyloma Of Cornea

  • Congenital Staphyloma
Kenny-Caffey Syndrome

  • Kenny Syndrome
Cribriform Carcinoma

  • Ductal Carcinoma, Cribriform Type

  • Carcinoma Cribriform

  • Carcinoma, Cribriform
Dystonia

  • Dystonic Disease

  • Dystonic Disorder

  • Dystonia Disorders

  • Neuroleptic Dyskinesia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05338 GCNA Human Pre-designed siRNA Set A Pre-designed Set / Unkown