GlcB-IN-1
GlcB-IN-1 is an inhibitor of Mycobacterium malate synthase (GlcB) with an IC50 of 1.05 μM. GlcB-IN-1 can be used for the research of tuberculosis.
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- CAS No.: 1346745-52-5
- Formule: C12H9NO4
- Masse moléculaire:231.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
GlcB-IN-1 (compound 19) binds to malate synthase (GlcB) from Mycobacterium tuberculosis, and the resulting complex retains the closed active site lid and the "inward" conformation of the CoA-binding loop, forming a weak hydrogen bond with Met-631[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1346745-52-5
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Masse moléculaire 231.20
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Formule C12H9NO4
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SMILES
O=C(/C=C(C(O)=O)\O)C1=CNC2=CC=CC=C21
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)