TMPRSS11A - transmembrane serine protease 11A Gene

Also Known as HESP; ECRG1; HATL1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 339967

About TMPRSS11A

Cytogenetic location: 4q13.2 Genomic coordinates (GRCh38): 4:67,909,395-67,963,493 (from NCBI)

This gene has 3 transcripts (splice variants), 534 orthologues and 17 paralogues. Restricted expression toward esophagus (RPKM 55.7).

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMPRSS11A Products (2)

mRNA Protein Name
NM_001114387.2 NP_001107859.1 transmembrane protease serine 11A isoform 2
NM_182606.4 NP_872412.3 transmembrane protease serine 11A isoform 1
Protein Preferred Names Protein Names

transmembrane protease serine 11A

  • airway trypsin-like protease 1

Related Diseases

Diseases Alias
Iron-Refractory Iron Deficiency Anemia

  • IRIDA

  • Anemia, Hypochromic Microcytic, With Defect In Iron Metabolism

  • Iron-Handling Disorder, Hereditary

  • Pseudo-Iron-Deficiency Anemia

  • Irida Syndrome

  • Hereditary Iron-Handling Disorder

  • Hypochromic Microcytic Anemia With Defect In Iron Metabolism

  • Anemia, Iron Deficiency, Iron-Refractory
Esophageal Cancer

  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus
Ichthyosis

  • Ichthyoses

  • Non-Syndromic Ichthyosis

  • Congenital Ichthyosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14763 TMPRSS11A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMPRSS11A VGNC VGNC:47628
Rattus norvegicus TMPRSS11A RGD RGD:1596322
Macaca mulatta TMPRSS11A VGNC VGNC:79673
Bos taurus TMPRSS11A VGNC VGNC:55081
Felis catus TMPRSS11A VGNC VGNC:66381
Mus musculus TMPRSS11A MGD MGI:2684853
Others TMPRSS11A NCBI