IHMT-15130
IHMT-15130 is a highly potent irreversible BMX kinase inhibitor (IC50=1.47 nM). IHMT-15130 inhibits the secretion of inflammatory cytokines, blocks inflammatory signaling pathways, and alleviates Angiotensin II-induced myocardial hypertrophy in mice. IHMT-15130 is promising for research of myocardial hypertrophy.
For research use only. We do not sell to patients.
- Formula: C22H17F3N6O2
- Molecular Weight:454.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 454.40
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Formula C22H17F3N6O2
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SMILES
O=C(CC1=CC(NC(C=C)=O)=CC=C1)NC2=CNN=C2C3=NC4=CC(C(F)(F)F)=CC=C4N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)