Lrrtm2 - leucine rich repeat transmembrane neuronal 2 Gene

Also Known as mKIAA0416; C630011A14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107065

Summary

Predicted to enable neurexin family protein binding activity. Acts upstream of or within several processes, including long-term synaptic potentiation; negative regulation of receptor internalization; and positive regulation of synapse assembly. Predicted to be located in excitatory synapse. Predicted to be integral component of membrane. Predicted to be active in GABA-ergic synapse and extracellular space. Predicted to be integral component of postsynaptic specialization membrane. Is expressed in neural tube and neural tube lateral wall. Orthologous to human LRRTM2 (leucine rich repeat transmembrane neuronal 2). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm2 Products (1)

mRNA Protein Name
NM_178005.4 NP_821072.1 leucine-rich repeat transmembrane neuronal protein 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within long-term synaptic potentiation IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within negative regulation of receptor internalization IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within synapse organization IGI
IGI: Inferred from genetic interaction
21788371 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 2

  • leucine-rich repeat transmembrane neuronal 2 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07842 LRRTM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrtm2 NCBI NCBI:26045