Pdxp - pyridoxal (pyridoxine, vitamin B6) phosphatase Gene

Also Known as PLPP; 1600027H05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57028

Summary

Enables magnesium ion binding activity; protein homodimerization activity; and pyridoxal Phosphatase activity. Involved in dephosphorylation and pyridoxal phosphate catabolic process. Located in cell-cell junction. Is expressed in alimentary system; eye; limb; nervous system; and tail. Orthologous to human PDXP (pyridoxal Phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Pdxp Products (1)

mRNA Protein Name
NM_020271.3 NP_064667.2 chronophin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables magnesium ion binding IDA
IDA: Inferred from direct assay
24338687 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24338687 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
25783190 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
24338687 MGI
enables pyridoxal phosphatase activity IDA
IDA: Inferred from direct assay
24338473 MGI
Biological Process GO Annotation Evidence References Source
involved in dephosphorylation IDA
IDA: Inferred from direct assay
24338687 MGI
involved in pyridoxal phosphate catabolic process IDA
IDA: Inferred from direct assay
24338473 MGI
involved in pyridoxal phosphate catabolic process IMP
IMP: Inferred from mutant phenotype
30327125 MGI
involved in regulation of modification of postsynaptic structure IDA
IDA: Inferred from direct assay
27212638 MGI
involved in regulation of modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
27212638 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27212638 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27212638 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
27212638 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
27212638 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chronophin

  • PLP phosphatase

  • PLP-phosophatase

  • chronophilin

  • pyridoxal 5'-phosphate phosphatase

  • pyridoxal phosphate phosphatase

Recombinant Pdxp Proteins

Cat. No. Product Name Accession Purity
HY-P71768 PLP phosphatase Protein, Mouse (P.pastoris, His) P60487 (M1-D292) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10298 PDXP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18631 Pdxp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25117 Pdxp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdxp NCBI NCBI:57026