Msln - mesothelin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60333

Summary

Involved in pancreas development. Located in cell surface and extracellular space. Human ortholog(s) of this gene implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human MSLN (Mesothelin). [provided by Alliance of Genome Resources, Apr 2022]

Msln Products (1)

mRNA Protein Name
NM_031658.1 NP_113846.1 mesothelin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Referencias Source
involved in pancreas development IEP
IEP: Inferred from expression pattern
18505465 RGD
Cellular Component GO Annotation Evidence Referencias Source
located in cell surface IDA
IDA: Inferred from direct assay
18294289 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
18294289 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mesothelin

  • ERC/mesothelin

  • pre-pro-megakaryocyte-potentiating factor

  • protein expressed in renal carcinoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Referencia número Nombre del producto Efecto
Pureza Phase
HY-P99006 Amatuximab Inhibitor 99.90% Phase 2
HY-P99352 Anetumab Inhibitor 98.78% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-P11058 OVA(250-264) 98.14% Unkown
HY-185561 Misitatug blivedotin / Unkown
HY-171269 Anetumab-MMAE / Unkown
HY-P11025 TMVP1446 / Unkown
HY-P11026 DOTA-TMVP1446 / Unkown
HY-RS08719 MSLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17193 Msln Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23644 Msln Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-P990833 Anti-Mesothelin Antibody (YP218) Inhibitor 95.00% Unkown
HY-P990929 Misitatug 99.00% Unkown
HY-P99663 Inezetamab Inhibitor 99.77% Unkown
HY-P991315 Anti-MSLN/Mesothelin (h7D9.v3) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msln NCBI NCBI:10232