Ufl1 - UFM1 specific ligase 1 Gene

Also Known as Rcad; Maxer; Kiaa0776; mKIAA0776; 1810074P20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67490

Summary

Predicted to enable UFM1 Ligase activity and protein kinase binding activity. Involved in hemopoiesis; positive regulation of autophagy; and response to endoplasmic reticulum stress. Acts upstream of or within positive regulation of glial cell proliferation; regulation of gene expression; and response to L-glutamate. Located in cytoplasm and neuron projection. Is expressed in cerebellum; cerebral cortex; and liver. Orthologous to human UFL1 (UFM1 specific Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ufl1 Products (2)

mRNA Protein Name
NM_001355512.1 NP_001342441.1 E3 UFM1-protein ligase 1
NM_026194.5 NP_080470.2 E3 UFM1-protein ligase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21494687 MGI
Biological Process GO Annotation Evidence References Source
involved in erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
25952549 MGI
involved in hematopoietic stem cell differentiation IMP
IMP: Inferred from mutant phenotype
25952549 MGI
involved in negative regulation of T cell activation IMP
IMP: Inferred from mutant phenotype
38377992 MGI
involved in positive regulation of autophagy IMP
IMP: Inferred from mutant phenotype
25952549 MGI
acts upstream of or within positive regulation of glial cell proliferation IDA
IDA: Inferred from direct assay
20531390 MGI
acts upstream of or within positive regulation of glial cell proliferation IMP
IMP: Inferred from mutant phenotype
20531390 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20531390 MGI
acts upstream of or within response to L-glutamate IMP
IMP: Inferred from mutant phenotype
20531390 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
25952549 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20531390 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
20531390 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 UFM1-protein ligase 1

  • E3 UFM1-protein transferase 1

  • multiple alpha-helix protein located at ER

  • regulator of C53/LZAP and DDRGK1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19395 Ufl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183257 ATI-1 / Unkown
HY-RS15415 UFL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25887 Ufl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ufl1 NCBI NCBI:23376