PAQR4 - progestin and adipoQ receptor family member 4 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 124222

About PAQR4

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,969,348-2,973,484 (from NCBI)

This gene has 5 transcripts (splice variants), 257 orthologues and 10 paralogues. Broad expression in brain (RPKM 16.0), bone marrow (RPKM 6.3) and 22 other tissues.

Summary

Predicted to enable signaling receptor activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

PAQR4 Products (5)

mRNA Protein Name
NM_001284511.2 NP_001271440.1 progestin and adipoQ receptor family member 4 isoform 2
NM_001284512.2 NP_001271441.1 progestin and adipoQ receptor family member 4 isoform 3
NM_001284513.2 NP_001271442.1 progestin and adipoQ receptor family member 4 isoform 4
NM_001324118.2 NP_001311047.1 progestin and adipoQ receptor family member 4 isoform 5
NM_152341.5 NP_689554.2 progestin and adipoQ receptor family member 4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables molecular adaptor activity IDA
IDA: Inferred from direct assay
38961186 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in protein stabilization IDA
IDA: Inferred from direct assay
38961186 GOA
involved in regulation of ceramide biosynthetic process IDA
IDA: Inferred from direct assay
32291319 GOA
Cellular Component GO Annotation Evidence Referencias Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
32291319 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PAQR4 Protein Structure

HlyIII

HlyIII: Haemolysin-III related (43 - 251)

  • 0
  • 100
  • 200
  • 273 a.a.
Protein Preferred Names Protein Names

progestin and adipoQ receptor family member 4

  • progestin and adipoQ receptor family member IV

Related Diseases

Diseases Alias
Myositis Fibrosa

  • Interstitial Myositis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS10032 PAQR4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PAQR4 VGNC VGNC:80639
Canis familiaris PAQR4 VGNC VGNC:44260
Mus musculus PAQR4 MGD MGI:1923748
Bos taurus PAQR4 VGNC VGNC:32576
Rattus norvegicus PAQR4 RGD RGD:1309533
Macaca mulatta PAQR4 VGNC VGNC:75683
Others PAQR4 NCBI