Ndst1 - N-deacetylase and N-sulfotransferase 1 Gene

Also Known as Hsst; N-HSST

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29633

Summary

Enables [heparan sulfate]-glucosamine N-sulfotransferase activity and heparan sulfate N-deacetylase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ndst1 Products (1)

mRNA Protein Name
NM_024361.2 NP_077337.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables [heparan sulfate]-glucosamine N-sulfotransferase activity IDA
IDA: Inferred from direct assay
1379236 RGD
enables heparan sulfate N-deacetylase activity IDA
IDA: Inferred from direct assay
8483907 RGD
enables heparan sulfate N-deacetylase activity IMP
IMP: Inferred from mutant phenotype
9915799 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
9915799 RGD
involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IDA
IDA: Inferred from direct assay
1379236 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

  • Golgi heparan sulfate N-deacetylase/N-sulfotransferase

  • HSNST 1

  • N-HSST 1

  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

  • N-deacetylase/N-sulfotransferase 1

  • N-heparan sulfate sulfotransferase 1

  • NDST-1

  • [Heparan sulfate]-glucosamine N-sulfotr

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS09118 NDST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20062 Ndst1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26566 Ndst1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndst1 NCBI NCBI:3340