ITGAE - integrin subunit alpha E Gene

Also Known as CD103; HUMINAE

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3682

About ITGAE

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:3,714,628-3,801,188 (from NCBI)

This gene has 9 transcripts (splice variants), 164 orthologues and 17 paralogues. Ubiquitous expression in bone marrow (RPKM 3.1), small intestine (RPKM 2.6) and 25 other tissues.

Summary

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha Integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 Integrin, this protein forms the E-cadherin binding Integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]

ITGAE Products (1)

mRNA Protein Name
NM_002208.5 NP_002199.3 integrin alpha-E precursor

ITGAE Protein Structure

VWA

VWA: von Willebrand factor type A domain (203 - 376)

Integrin_alpha2

Integrin_alpha2: Integrin alpha (676 - 1082)

Integrin_alpha

Integrin_alpha: Integrin alpha cytoplasmic region (1148 - 1159)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1179 a.a.
Protein Preferred Names Protein Names

integrin alpha-E

  • HML-1 antigen

ITGAE Antibodies

Referencia número Nombre del producto Aplicación Reactivity
HY-P81498 CD103 Antibody (YA1243) IHC-P Human
HY-P81498A CD103 Antibody (YA1243)(PBS only) IHC-P Human
HY-P83306 CD103 Antibody (YA3051) IHC-P Human

Related Diseases

Diseases Alias
Enteropathy-Associated T-Cell Lymphoma

  • Intestinal T-Cell Lymphoma

  • Eatcl

  • High-Grade Pleomorphic Peripheral T-Cell Lymphoma

  • Eatl

  • Ettl

  • Enteropathy-Type T-Cell Lymphoma

  • Enteropathy Type Intestinal T-Cell Lymphoma
Mycosis Fungoides

  • Mycosis Fungoides Lymphoma

  • Alibert-Bazin Syndrome

  • Granuloma Fungoides

  • Classic Mycosis Fungoides

  • Mycosis Fungoides, Alibert-Bazin Type
Hairy Cell Leukemia

  • Hcl-V

  • Hairy Cell Leukemia Variant

  • Hairy Cell Leukaemia Variant

  • Hcl

  • Leukemic Reticuloendotheliosis

  • Leukemic Reticuloendotheliosis Variant

  • Prolymphocytic Variant Of Hcl

  • Prolymphocytic Variant Of Hairy Cell Leukemia

  • Leukemia Hairy Cell

  • Leukemia, Hairy Cell

  • Leukaemic Reticuloendotheliosis

  • Lre - [Leukemic Reticuloendotheliosis]

  • Hairy-Cell Leukaemia, Nos

  • Hcl - [Hairy Cell Leukaemia]

  • Hairy-Cell Leukaemia Without Mention Of Remission
Spleen Cancer

  • Spleen Neoplasm

  • Splenic Neoplasm

  • Splenic Neoplasms

  • Malignant Splenic Tumor

  • Malignant Tumour Of Spleen

  • Tumor Of Spleen

  • Malignant Neoplasm Of Spleen
Splenic Marginal Zone Lymphoma

  • Smzl

  • Splenic Marginal Zone B-Cell Lymphoma
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

  • Cutaneous T-Cell Lymphoma

  • Cutaneous T Cell Lymphoma

  • Lymphoma, T-Cell, Cutaneous

  • Ctcl

  • Lymphoma T-Cell Cutaneous
B-Cell Prolymphocytic Leukemia

  • B Cell Prolymphocytic Leukemia

  • Prolymphocytic Leukemia, B-Cell Type

  • B-Pll

  • Doid:0081041

  • Leukemia, Prolymphocytic, B-Cell

  • Pll- [Prolymphocytic Leukaemia]

  • Prolymphocytic Leukaemia

  • Prolymphocytic Leukaemia Of B-Cell Type Without Mention Of Remission
Inflammatory Bowel Disease

  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory
Cystinosis

  • Cystine Storage Disease

  • Cystine Diathesis

  • Cystine Disease

  • Cystinoses

  • Protein Defect Of Cystin Transport

  • Cystin Transport, Protein Defect Of

  • Nephropathic Cystinosis

  • Protein Defect Of Cystine Transport
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Mesenteric Lymphadenitis

  • Mesenteric Adenitis
Splenic Disease

  • Splenic Diseases

  • Dyssplenism

  • Spleen Disease

  • Abnormality Of The Spleen

  • Spleen Diseases
Sarcoid Meningitis

  • Meningitis In Sarcoidosis
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Autoimmune Disease Of Gastrointestinal Tract
Celiac Disease 1

  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome
Crohn'S Disease

  • Crohn Disease

  • Pediatric Crohn'S Disease

  • Regional Enteritis

  • Crohn'S Disease Of Large Bowel

  • Granulomatous Colitis

  • Enteritis, Granulomatous

  • Enteritis

  • Crohn'S Disease Of Colon

  • Colitis, Granulomatous

  • Crohn'S Enteritis

  • Enteritis, Regional

  • Ileitis

  • Adenoviral Enteritis

  • Acute Gastroenteropathy Due To Norwalk Agent

  • Viral Gastroenteritis Due To Norwalk Agent

  • Winter Vomiting

  • Epidemic Winter Vomiting Disease

  • Small Round Structured Virus Enteritis

  • Epidemic Vomiting Syndrome

  • Epidemic Vomiting

  • Epidemic Nausea

  • Epidemic Viral Gastroenteritis Due To Norwalk Virus

  • Noroviral Enteritis

  • Crohn Disease Nos

  • Crohns

  • Cd - [Crohn'S Disease]

  • Regional Enteritis Of Bowel

  • Crohn'S Regional Enteritis

  • Cobble-Stone Appearance Of Intestine

  • Intestinal Ulcer And Erosion Due To Crohn Disease

  • Granulomatous Enteritis
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
Skin Disease

  • Skin Diseases

  • Genodermatosis

  • Abnormality Of The Skin

  • Skin Diseases, Genetic

  • Skin And Subcutaneous Tissue Disease

  • Dermatologic Disorders
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS06958 ITGAE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ITGAE VGNC VGNC:42131
Bos taurus ITGAE VGNC VGNC:30321
Felis catus ITGAE VGNC VGNC:67847
Mus musculus ITGAE MGD MGI:1298377
Rattus norvegicus ITGAE RGD RGD:621644
Others ITGAE NCBI