CD103 Antibody (YA1243)
(Synonyms: Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD103; ITGAE; Integrin alpha E)CD103 Antibody (YA1243) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD103.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.135.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 100-1:200 |
Product Details
CD103 Antibody (YA1243) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD103.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
A synthesized peptide derived from human CD103
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.135.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD103 is an Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is expressed on a subset of T lymphocytes called intraepithelial lymphocytes, which are located between mucosal epithelial cells.
Induction:Integrin alpha-E/beta-7 is induced by TGFB1 -
Subunit
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7
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SwissProt ID
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Synonyms
Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD103; ITGAE; Integrin alpha E
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Research Field
Signal Transduction
Documentation