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MGARP - mitochondria localized glutamic acid rich protein Gene

Also Known as OSAP; HUMMR; CESP-1; C4orf49

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 84709

About MGARP

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:139,266,165-139,280,225 (from NCBI)

This gene has 1 transcript (splice variant) and 114 orthologues. Biased expression in adrenal (RPKM 112.3) and ovary (RPKM 9.8).

Summary

Predicted to be involved in several processes, including axonal transport; cellular response to hormone stimulus; and protein targeting to mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MGARP Products (1)

mRNA	Protein	Name
NM_032623.4	NP_116012.2	protein MGARP

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Referencias	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19528298	GOA

Cellular Component GO Annotation	Evidence	Referencias	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	16565373	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MGARP Protein Structure

AIF-MLS

0
100
200
240 a.a.

Protein Preferred Names	Protein Names
protein MGARP	corneal endothelium-specific protein 1

MGARP Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Referencias
Intra	MGARP	Q8TDB4	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	MGARP	Q8TDB4	PSEN1	Homo sapiens	P49768-2	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	PSEN1	Homo sapiens	P49768-2	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	PSEN1	Homo sapiens	P49768-2	Y2H Array	32814053
Intra	MGARP	Q8TDB4	MECP2	Homo sapiens	P51608	Y2H Array	32814053
Intra	MGARP	Q8TDB4	MECP2	Homo sapiens	P51608	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	MECP2	Homo sapiens	P51608	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	APP	Homo sapiens	P05067-2	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	APP	Homo sapiens	P05067-2	Y2H Array	32814053
Intra	MGARP	Q8TDB4	APP	Homo sapiens	P05067-2	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	APBB2	Homo sapiens	Q92870-2	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	APBB2	Homo sapiens	Q92870-2	Y2H Array	32814053
Intra	MGARP	Q8TDB4	APBB2	Homo sapiens	Q92870-2	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	TOR1A	Homo sapiens	O14656-2	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	TOR1A	Homo sapiens	O14656-2	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	TOR1A	Homo sapiens	O14656-2	Y2H Array	32814053
Intra	MGARP	Q8TDB4	ALS2	Homo sapiens	A0A0S2Z5Q7	Y2H Array	32814053
Intra	MGARP	Q8TDB4	ALS2	Homo sapiens	A0A0S2Z5Q7	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	ALS2	Homo sapiens	A0A0S2Z5Q7	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	SMN1	Homo sapiens	Q16637	Y2H Array	32814053
Intra	MGARP	Q8TDB4	SMN1	Homo sapiens	Q16637	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	SMN1	Homo sapiens	Q16637	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	MGARP	Q8TDB4	A2M	Homo sapiens	P01023	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	A2M	Homo sapiens	P01023	Y2H Array	32814053
Intra	MGARP	Q8TDB4	A2M	Homo sapiens	P01023	Y2H Pooling	32814053
Intra	MGARP	Q8TDB4	OPTN	Homo sapiens	Q96CV9	Validated Y2H	32814053
Intra	MGARP	Q8TDB4	OPTN	Homo sapiens	Q96CV9	Y2H Array	32814053
Intra	MGARP	Q8TDB4	OPTN	Homo sapiens	Q96CV9	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Referencia número	Nombre del producto	Efecto	Pureza	Rare Diseases
HY-RS08398	MGARP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MGARP	RGD	RGD:1586369
Bos taurus	MGARP	VGNC	VGNC:31447
Mus musculus	MGARP	MGD	MGI:1914999
Canis familiaris	MGARP	VGNC	VGNC:43212
Macaca mulatta	MGARP	VGNC	VGNC:74623
Others	MGARP	NCBI