Hemocyanin
Based on 1 Customer Validation
Hemocyanin is an extracellular giant copper-containing glycoprotein. Hemocyanin can be found in the hemolymph of both mollusk and arthropod. Hemocyanin is responsible for oxygen transport. Hemocyanin is also involved in several physiological processes, such as energy storage, osmoregulation, molt cycle and exoskeleton formation. Hemocyanin in shrimp can enhance its immune response by modulating the p38 MAPK pathway. Hemocyanin from Penaeus monodon could act as an antiviral agent against a variety of viruses including DNA and RNA viruses. Hemocyanin from horseshoe crab Carcinoscorpius rotundicauda could possess a strong antimicrobial defense by the production of ROS activated with microbial proteases. Hemocyanin from L. vannamei would be effective against cervical cancer cell growth.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 95%
- No. CAS: 9013-72-3
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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Human Endogenous Metabolite |
Hemocyanin (10-50 μg/mL; 48 h) from Litopenaeus vannamei exhibits antiproliferative activity against HeLa cells (57-71% inhibition)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HeLa cells, 293T cells
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Concentration:10, 20, 30, 40, 50 μg/mL
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Incubation Time:24 h, 48 h
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Result:Inhibited HeLa cell growth by 57-71% at 10-50 μg/mL for 48 h (p < 0.01). Showed no significant growth inhibition in 293T cells under the same conditions.
Chemical Information
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No. CAS 9013-72-3
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Appearance Solid
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Color Off-white to gray
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SMILES
[Hemocyanin]
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Structure Classification
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Initial Source
crayfish
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvente y solubilidad
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Zheng L, et al. Hemocyanin from Shrimp Litopenaeus vannamei Has Antiproliferative Effect against HeLa Cell In Vitro. PLoS One. 2016 Mar 23;11(3):e0151801. doi: 10.1371/journal.pone.0151801. PMID: 27007573; PMCID: PMC4805270. [Content Brief]
[2]. Cheng J, et al. Hemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK. Virulence. 2025;16(1):2546066. [Content Brief]
[3]. Decker H, et al. Minireview: Recent progress in hemocyanin research. Integr Comp Biol. 2007;47(4):631-644. [Content Brief]
[4]. Antonova O, et al. In vitro antiproliferative effect of Helix aspersa hemocyanin on multiple malignant cell lines. Z Naturforsch C J Biosci. 2014;69(7-8):325-334. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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