Quilostigmine
Quilostigmine (HP-290) is an orally active Physostigmine (HY-N6608) analogue, acetylcholinesterase (IC50: 148 nM for rat brain acetylcholinesterase) inhibitor. Quilostigmine has a long-lasting effect on tremors. Quetiapine can be used in the research of Alzheimer's disease.
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- No. CAS: 139314-01-5
- Fòrmula: C23H27N3O2
- Peso molecular:377.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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AChE |
Chemical Information
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No. CAS 139314-01-5
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Peso molecular 377.48
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Fòrmula C23H27N3O2
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SMILES
O=C(N1CC2=C(C=CC=C2)CC1)OC3=CC4=C(N(C)[C@]5([H])[C@@]4(C)CCN5C)C=C3
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Synonyms
HP-290; NXX-066
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Dahlin M, Björk E. Nasal administration of a physostigmine analogue (NXX-066) for Alzheimer's disease to rats. Int J Pharm. 2001 Jan 16;212(2):267-74. [Content Brief]
[2]. Snape MF, et al. A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology. 1999 Jan;38(1):181-93. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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