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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
MCC
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "MCC" in MCE Product Catalog:
Target:
Áreas de investigación:
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 .
486
486 Publications Verification
Synonyms: CP-456773; CRID3
Target:
Áreas de investigación:
MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
486
486 Publications Verification
Synonyms: CP-456773 sodium; CRID3 sodium salt
Target:
Áreas de investigación:
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
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1 Cited Publications
Synonyms: Lys-Nε-MCC-DM1
Target:
Áreas de investigación:
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer .
Synonyms: MCC7840
Target:
Áreas de investigación:
Emlenoflast (MCC7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast can be used for the research of inflammatory diseases .
Target:
Áreas de investigación:
MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues .
Referencia número: HY-174279
No. CAS: 3052836-65-1
Target:
Áreas de investigación:
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment .
Synonyms: MCC-555; Isaglitazone
Target:
Áreas de investigación:
Netoglitazone (MCC-555) is an orally active PPARγ ligand with an EC50 of 8 μM. Netoglitazone mediates cell type-specific functional regulation, and modulates the transcriptional activity of PPARγ as a full agonist, partial agonist or antagonist. Netoglitazone induces adipogenesis, inhibits osteoblastogenesis, alters the weight of extramedullary fat depots and enhances insulin sensitivity. Netoglitazone reduces blood glucose levels. Netoglitazone can be used in research related to type 2 diabetes and non-insulin-dependent diabetes mellitus .
Synonyms: MCC7840 sodium
Target:
Áreas de investigación:
Emlenoflast (MCC7840) sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast sodium can be used for the research of inflammatory diseases .
Referencia número: HY-P991661
No. CAS: 1607838-85-6
Áreas de investigación:
Synonyms: MCC-135
Target:
Áreas de investigación:
Caldaret is an intracellular Ca 2+ handling modulator that acts through reverse mode Na +/Ca 2+ exchanger inhibition.
Referencia número: HY-101982A
Pureza: 98.18%
Synonyms: (Rac)-Lys-Nε-MCC-DM1
Target:
Áreas de investigación:
(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1 .
Synonyms: LY582563; MCC-478
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect .
Referencia número: HY-141143
No. CAS: 2504147-59-3
Target:
Áreas de investigación:
MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Referencia número: HY-128959
No. CAS: 721945-30-8
Target:
Áreas de investigación:
MCC-Modified Daunorubicinol is a drug-Linker conjugates for ADC, which is composed of Modified Daunorubicinol (DNA topoisomerase II inhibitor) and MCC (ADC linker) linked .
Referencia número: HY-W800787
No. CAS: 384847-49-8
18:1 PE MCC is a reactive phospholipid containing a maleimide group. 18:1 PE MCC forms covalent bonds with thiol-modified chondroitin sulfate (CS) via thiol-maleimide reaction, and anchors CS to the surface of lipid membranes. 18:1 PE MCC is applicable to glycocalyx model construction and lipid membrane biophysics research .
Referencia número: HY-12815R
No. CAS: 210826-40-7
Synonyms: CP-456773 (Standard); CRID3 (Standard)
Áreas de investigación:
MCC950 (Standard) is the analytical standard of MCC950. This product is intended for research and analytical applications. MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
Referencia número: HY-119306
No. CAS: 181238-67-5
Target:
Áreas de investigación:
MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent .
Referencia número: HY-14936
No. CAS: 187602-11-5
Synonyms: MCC-977
Target:
Áreas de investigación:
Sofigatran (MCC-977) is an orally active factor IIa (thrombin) inhibitor, acts as an anticoagulant. Sofigatran is used for the research of cardiovascular disease .
Referencia número: HY-W800786
No. CAS: 384832-87-5
Synonyms: N-MCC-PE
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
