YSK 12C4
Based on 1 Customer Validation
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.31%
- No. CAS: 1829511-70-7
- Fòrmula: C43H81NO
- Peso molecular:628.11
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Almacenamiento:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Chemical Information
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Immunology/Inflammation Compound Library
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Metabolism/Protease Compound Library
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HY-L001V
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High-Throughput Bioactive Compound Library
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Liposome Library
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Ionizable Lipid Compound Library
HY-L251
Actividad biológica
A multifunctional envelope-type nanodevice (MEND) containing YSK 12C4 lipid (YSK12-MEND) can be used to deliver siRNA to mouse DC15. YSK 12C4 is an ionizable-cationic lipid containing unsaturated carbon chains, which facilitate efficient endosomal escape. The use of the YSK12-MEND resulted in a gene silencing efficiency in excess of 90%, with an ED50 of 1.5 nM in mouse DC15[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1829511-70-7
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Appearance Oil
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Peso molecular 628.11
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Fòrmula C43H81NO
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCN(C)C)(O)CCCCCCCC/C=C\C/C=C\CCCCC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (260 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YSK 12C4 Related Classifications
HY-160852 Related Classifications
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