FGFR3 - fibroblast growth factor receptor 3 Gene

Sus scrofa

Gene ID: 100514115 | Gene type: protein coding

About FGFR3

Primary_assembly 8: 879,159-894,964 forward strand.Sscrofa11.1:CM000819.5

This gene has 4 transcripts (splice variants), 191 orthologues and 52 paralogues. Biased expression in kidney (RPKM 23.8), liver (RPKM 17.1) and 3 other tissues.

FGFR3 Products(11)

mRNA	Protein	Name
XM_021100900.1	XP_020956559.1	fibroblast growth factor receptor 3 isoform X3
XM_021100898.1	XP_020956557.1	fibroblast growth factor receptor 3 isoform X1
XM_021100907.1	XP_020956566.1	fibroblast growth factor receptor 3 isoform X9
XM_021100904.1	XP_020956563.1	fibroblast growth factor receptor 3 isoform X6
XM_021100905.1	XP_020956564.1	fibroblast growth factor receptor 3 isoform X7
XM_021100902.1	XP_020956561.1	fibroblast growth factor receptor 3 isoform X4
XM_021100899.1	XP_020956558.1	fibroblast growth factor receptor 3 isoform X2
XM_021100908.1	XP_020956567.1	fibroblast growth factor receptor 3 isoform X10
XM_021100906.1	XP_020956565.1	fibroblast growth factor receptor 3 isoform X8
XM_021100909.1	XP_020956568.1	fibroblast growth factor receptor 3 isoform X11
XM_021100903.1	XP_020956562.1	fibroblast growth factor receptor 3 isoform X5

FGFR3 Protein Structure

IgI_2_FGFR

IgI_3_FGFR

PKc_like

0
200
400
600
806 a.a.

Protein Preferred Names

Protein Names

fibroblast growth factor receptor 3

Related Agents

Approval

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13311	Infigratinib		99.82%	Yes
HY-109099	Pemigatinib	Inhibitor	99.84%	Yes
HY-10209	Masitinib		99.94%	Yes
HY-13311A	Infigratinib phosphate	Inhibitor	99.59%	Yes
HY-P3503	Vosoritide	Inhibitor	99.89%	Unkown
HY-10209A	Masitinib mesylate		99.98%	Yes

Clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13330	Fexagratinib	Inhibitor	99.92%	Phase 3
HY-50905	Dovitinib	Inhibitor	99.88%	Phase 3
HY-100019	Rogaratinib	Inhibitor	99.86%	Phase 3
HY-B0062	Dovitinib lactate hydrate	Inhibitor	/	Phase 3
HY-13304	LY2874455	Inhibitor	99.14%	Phase 2
HY-19957	Zoligratinib	Inhibitor	99.76%	Phase 2
HY-109082	Cevidoplenib	Inhibitor	99.58%	Phase 2
HY-101466A	E7090 succinate	Inhibitor	99.17%	Phase 2
HY-10032	PF 477736	Inhibitor	99.04%	Phase 1
HY-119367	ODM-203	Inhibitor	99.62%	Phase 1
HY-101768	PRN1371	Inhibitor	99.78%	Phase 1
HY-156632	Resigratinib	Inhibitor	99.53%	Phase 1

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99384	Vofatamab	Inhibitor	99.9%	Phase 2
HY-P99823	Recifercept		97.10%	Phase 2

Pre-clinical Phase

Bioactive Molecules (84)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-159642	Dabogratinib	Inhibitor	99.90%	Unkown
HY-135960	BO-264		99.76%	Unkown
HY-18602	FIIN-2	Inhibitor	99.32%	Unkown
HY-15813	FIIN-1	Inhibitor	99.04%	Unkown
HY-101466	E7090	Inhibitor	98.11%	Unkown
HY-107194	NSC12		99.27%	Unkown
HY-145231	FGFR2-IN-2	Inhibitor	98.25%	Unkown
HY-P3695	VSPPLTLGQLLS	Inhibitor	99.53%	Unkown
HY-148779	FGFR3-IN-5	Inhibitor	99.16%	Unkown
HY-18603	FIIN-3	Inhibitor	99.01%	Unkown
HY-175743	TYRA-200	Inhibitor	98.06%	Unkown
HY-145895	SNIPER(TACC3)-11	Inhibitor	99.58%	Unkown
HY-108933	JK-P3	Inhibitor	99.75%	Unkown
HY-RS04919	Fgfr3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04918	FGFR3 Human Pre-designed siRNA Set A		/	Unkown
HY-W070306	PDK1-IN-1	Inhibitor	99.95%	Unkown
HY-13311S	Infigratinib-d3	Inhibitor	98.90%	Unkown
HY-145043	FGFR-IN-1	Inhibitor	99.46%	Unkown
HY-174981	LC-MF-4		/	Unkown
HY-RS04920	Fgfr3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-122833	FGFR3-IN-10	Inhibitor	/	Unkown
HY-122888	MPT0L145		/	Unkown
HY-123134	FIIN-4	Inhibitor	/	Unkown
HY-142921	FGFR-IN-2	Inhibitor	/	Unkown
HY-146541	FGFR4-IN-10	Inhibitor	/	Unkown
HY-147713	FGFR3-IN-1	Inhibitor	/	Unkown
HY-147714	FGFR3-IN-2	Inhibitor	/	Unkown
HY-147715	FGFR3-IN-3	Inhibitor	/	Unkown
HY-148778	FGFR3-IN-4	Inhibitor	/	Unkown
HY-150652	FGFR-IN-8		/	Unkown
HY-151903S	FGFR2/3-IN-1	Inhibitor	/	Unkown
HY-152104	FGFR-IN-9	Inhibitor	/	Unkown
HY-152146	HDAC-IN-50		/	Unkown
HY-155028	FGFR-IN-11	Inhibitor	/	Unkown
HY-156790	FGFR3-IN-6	Inhibitor	/	Unkown
HY-156791	FGFR3-IN-7	Inhibitor	/	Unkown
HY-158010	FGFR3-IN-8	Inhibitor	/	Unkown
HY-158011	FGFR3-IN-9	Inhibitor	/	Unkown
HY-159642G	Dabogratinib (GMP)	Inhibitor	/	Unkown
HY-162577	FGFR-IN-14	Inhibitor	/	Unkown
HY-163273	FGFR4-IN-17	Inhibitor	/	Unkown
HY-170919	FGFR2/3-IN-2	Inhibitor	/	Unkown
HY-170934	BW710	Inhibitor	/	Unkown
HY-172921	FGFR-IN-18	Inhibitor	/	Unkown
HY-172922	FGFR-IN-19	Inhibitor	/	Unkown
HY-174154	INCB126503	Inhibitor	/	Unkown
HY-174974	ISM7594	Inhibitor	/	Unkown
HY-176547	FGFR2/3-IN-3	Inhibitor	/	Unkown
HY-177276	FGFR-IN-22	Inhibitor	/	Unkown
HY-178059	FGFR-IN-23		/	Unkown
HY-181152	FGFR3-IN-11	Inhibitor	/	Unkown
HY-181153	PROTAC FGFR3 Degrader-1	Degrader	/	Unkown
HY-181752	FGFR3-IN-12		/	Unkown
HY-182354	VEGFR2-IN-84	Inhibitor	/	Unkown
HY-182817	Len-604		/	Unkown
HY-182915	FGFR-IN-26	Inhibitor	/	Unkown
HY-183780	FGFR-IN-27		/	Unkown
HY-50905S	Dovitinib-d8	Inhibitor	/	Unkown
HY-E70718	FGFR3 G697C Recombinant Human Active Protein Kinase		/	Unkown
HY-E70719	FGFR3 K650E Recombinant Human Active Protein Kinase		/	Unkown
HY-E70720	FGFR3 K650M Recombinant Human Active Protein Kinase		/	Unkown
HY-E70721	FGFR4 N535K Recombinant Human Active Protein Kinase		/	Unkown
HY-E70722	FGFR4 V550E Recombinant Human Active Protein Kinase		/	Unkown
HY-E70814	FGFR2 C491S Recombinant Human Active Protein Kinase		/	Unkown
HY-E70815	FGFR2 K526E Recombinant Human Active Protein Kinase		/	Unkown
HY-E70816	FGFR2 K641N Recombinant Human Active Protein Kinase		/	Unkown
HY-E70817	FGFR2 K641R Recombinant Human Active Protein Kinase		/	Unkown
HY-E70818	FGFR2 K659M Recombinant Human Active Protein Kinase		/	Unkown
HY-E70819	FGFR2 K659N Recombinant Human Active Protein Kinase		/	Unkown
HY-E70820	FGFR2 L617V Recombinant Human Active Protein Kinase		/	Unkown
HY-E70821	FGFR2 M537I Recombinant Human Active Protein Kinase		/	Unkown
HY-E70822	FGFR2 N549H Recombinant Human Active Protein Kinase		/	Unkown
HY-E70823	FGFR2 N549K Recombinant Human Active Protein Kinase		/	Unkown
HY-E70824	FGFR2 R612T Recombinant Human Active Protein Kinase		/	Unkown
HY-E70825	FGFR2 V564F Recombinant Human Active Protein Kinase		/	Unkown
HY-E70826	FGFR2 V564I Recombinant Human Active Protein Kinase		/	Unkown
HY-E70827	FGFR2 V564L Recombinant Human Active Protein Kinase		/	Unkown
HY-E70828	FGFR3 V555L Recombinant Human Active Protein Kinase		/	Unkown
HY-E70829	FGFR3 V555M Recombinant Human Active Protein Kinase		/	Unkown
HY-N13841	2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose		/	Unkown
HY-P3695A	VSPPLTLGQLLS TFA	Inhibitor	/	Unkown
HY-159503A	Segigratinib hydrochloride	Inhibitor	/	Unkown
HY-174688	Human FGFR3 mRNA		/	Unkown
HY-W754878	Pemigatinib-d6	Inhibitor	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991106	IMC-D11	Inhibitor	98.51%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	FGFR3	NCBI	NCBI:2261
Mus musculus	FGFR3	NCBI	NCBI:14184

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