COLEC10 - collectin subfamily member 10 Gene

Homo sapiens

Also known as 3MC3; CLL1; CL-10; CL-34

Gene ID: 10584 | Gene type: protein coding

About COLEC10

Cytogenetic location: 8q24.12 Genomic coordinates (GRCh38): 8:118,952,263-119,108,455 (from NCBI)

This gene has 2 transcripts (splice variants), 193 orthologues, 4 paralogues and is associated with 3 phenotypes. Biased expression in liver (RPKM 17.0), placenta (RPKM 3.8) and 2 other tissues.

Summary

This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on Microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq, Jul 2008]

COLEC10 Products(2)

mRNA	Protein	Name
NM_001324095.2	NP_001311024.1	collectin-10 isoform 2
NM_006438.5	NP_006429.2	collectin-10 isoform 1 precursor

COLEC10 Protein Structure

Collagen

Lectin_C

0
100
200
277 a.a.

Protein Preferred Names

Protein Names

collectin-10

collectin liver 1

Related Diseases

Diseases

Alias

3mc Syndrome 3

3MC3	Malpuech Facial Clefting Syndrome
Facial Clefting Syndrome, Gypsy Type	Malpuech Facial Clefting Syndrome, Formerly
Facial Clefting Syndrome Gypsy Type	Malpuech Syndrome
3mc Syndrome, Type 3

3mc Syndrome

Craniofacial-Ulnar-Renal Syndrome	Malpuech Facial Clefting Syndrome
Oculopalatoskeletal Syndrome	Carnevale Syndrome
Michels Syndrome	Malpuech-Michels-Mingarelli-Carnevale Syndrome
Carnevale-Krajewska-Fischetto Syndrome	Craniosynostosis With Lid Anomalies
Malpuech Syndrome	Mingarelli Syndrome
Oculo-Skeletal-Abdominal Syndrome	Osa Syndrome
Ptosis Of Eyelids With Diastasis Recti And Hip Dysplasia	Ptosis-Strabismus-Rectus Abdominis Diastasis

3mc Syndrome 2

3MC2	Ptosis Of Eyelids With Diastasis Recti And Hip Dysplasia
Oculo-Skeletal-Abdominal Syndrome	Osa Syndrome
Carnevale Syndrome	Carnevale Syndrome, Formerly
Carnevale Krajewska Fischetto Syndrome	3mc Syndrome, Type 2

3mc Syndrome 1

Oculopalatoskeletal Syndrome	3MC1
Craniosynostosis With Lid Anomalies	Michels Syndrome, Formerly
Michels Syndrome	3mc Syndrome, Type 1

Blepharophimosis

Properdin Deficiency, X-Linked

Properdin Deficiency	PFD
CFPD	Properdin P Factor Deficiency
Complement Factor Properdin Deficiency	X-Linked Properdin Deficiency
Properdin Deficiency, Type I	Properdin Deficiency, Type 1
Properdin Deficiency Disease

Van Maldergem Syndrome 1

Cerebrofacioarticular Syndrome	VMLDS1
Van Maldergem Syndrome	Cerebro-Facio-Articular Syndrome
Van Maldergem Wetzburger Verloes Syndrome

Learning Disability

Learning Disabilities	Learning Disorders
Academic Skill Disorder	Learning Disorder

Craniosynostosis

Premature Closure Of Cranial Sutures	Craniostenosis
Craniosynostosis Syndrome	Cso
Craniosynostoses	Congenital Ossification Of Cranial Sutures
Congenital Ossification Of Sutures Of Skull	Craniostosis
Imperfect Fusion Of Skull	Congenital Imperfect Closure Skull
Imperfect Closure Skull	Premature Closure Cranium Sutures
Deficiency Of Craniofacial Axis

Radioulnar Synostosis

Radio-Ulnar Synostosis Type 1

Leukemia, Acute Myeloid

Acute Myeloid Leukemia	Leukemia, Acute Myelogenous
Acute Myelogenous Leukemia	AML
Leukemia, Acute Myeloid, Susceptibility To	Acute Myeloblastic Leukemia
Leukemia, Acute Myeloid, Reduced Survival In, Somatic	Acute Myeloid Leukaemia
Leukemia, Myelocytic, Acute	Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
Secondary Aml	Acute Myelocytic Leukemia
Acute Myeloid Leukemia, Somatic	Leukemia, Acute Myeloid, Somatic
Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic	Acute Myeloblastic Leukaemia
Acute Myelogenous Leukaemia	Aml - Acute Myeloid Leukemia
Acute Myeloid Leukemia With Cebpa Somatic Mutations	Aml With Cebpa Somatic Mutations
Inherited Acute Myeloid Leukemia	Familial Aml
Inherited Aml	Pure Familial Aml
Pure Familial Acute Myeloid Leukemia	Secondary Acute Myeloid Leukemia
Therapy-Related Aml And Myelodysplastic Syndrome	Acute Myeloid Leukemia, Secondary
Acute Non-Lymphoblastic Leukemia	Acute Non-Lymphocytic Leukemia
Acute Biphenotypic Leukemia	Acute Undifferentiated Leukemia
Acute Myeloblastic Leukaemia With Multilineage Dysplasia	Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission
Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03003	COLEC10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	COLEC10	RGD	RGD:1307149
Felis catus	COLEC10	VGNC	VGNC:81642
Canis familiaris	COLEC10	VGNC	VGNC:39488
Mus musculus	COLEC10	MGD	MGI:3606482
Bos taurus	COLEC10	VGNC	VGNC:53852
Macaca mulatta	COLEC10	VGNC	VGNC:71309
Macaca fascicularis	COLEC10	NCBI
Others	COLEC10	NCBI

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