Asl - argininosuccinate lyase Gene

Also Known as ASAL; 2510006M18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109900

Summary

Predicted to enable argininosuccinate lyase activity and identical protein binding activity. Acts upstream of or within ammonia assimilation cycle; locomotory behavior; and post-embryonic development. Predicted to be located in several cellular components, including cell body fiber; mitochondrial outer membrane; and perikaryon. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study argininosuccinic aciduria. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and argininosuccinic aciduria. Orthologous to human ASL (argininosuccinate lyase). [provided by Alliance of Genome Resources, Apr 2022]

Asl Products (1)

mRNA Protein Name
NM_133768.5 NP_598529.1 argininosuccinate lyase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22081021 MGI
Biological Process GO Annotation Evidence References Source
involved in L-arginine biosynthetic process IMP
IMP: Inferred from mutant phenotype
22081021 MGI
acts upstream of or within amino acid metabolic process IMP
IMP: Inferred from mutant phenotype
12559843 MGI
acts upstream of or within ammonia assimilation cycle IMP
IMP: Inferred from mutant phenotype
12559843 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
12559843 MGI
involved in positive regulation of nitric oxide biosynthetic process IMP
IMP: Inferred from mutant phenotype
22081021 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
12559843 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

argininosuccinate lyase

  • arginosuccinase

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0451A Dopamine hydrochloride Inhibitor 99.79% Unkown
HY-B0451 Dopamine Inhibitor 98.56% Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113284 Succinyladenosine 99.43% Unkown
HY-B0451AS4 Dopamine-d3 hydrochloride 99.88% Unkown
HY-B0451AS7 Dopamine-d5 hydrochloride Inhibitor 99.6% Unkown
HY-B0451AS Dopamine-d4 hydrochloride 99.99% Unkown
HY-B0451AS1 Dopamine-13C6 hydrochloride 98.71% Unkown
HY-B0451AS5 Dopamine-13C hydrochloride 99.74% Unkown
HY-RS01095 ASL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0451AS6 Dopamine-13C,15N hydrochloride 99.02% Unkown
HY-B0451AS2 Dopamine-d2 hydrochloride 99.6% Unkown
HY-B0451AS3 Dopamine-d2-1 hydrochloride / Unkown
HY-RS00418 ADSL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W752476 Succinyladenosine-13C4 / Unkown
HY-RS16982 Asl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18123 Adsl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23425 Asl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W416440 Esmolol acid hydrochloride Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asl NCBI NCBI:435