1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Succinyladenosine

Succinyladenosine  (Synonyms: N6-Succinyl adenosine)

Cat. No.: HY-113284 Purity: 99.60%
COA Handling Instructions

Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency.

For research use only. We do not sell to patients.

Succinyladenosine Chemical Structure

Succinyladenosine Chemical Structure

CAS No. : 4542-23-8

Size Price Stock Quantity
1 mg USD 390 In-stock
5 mg   Get quote  
10 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100–500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

383.31

Formula

C14H17N5O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO)([H])N2C3=NC=NC(N[C@H](C(O)=O)CC(O)=O)=C3N=C2

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (652.21 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6089 mL 13.0443 mL 26.0885 mL
5 mM 0.5218 mL 2.6089 mL 5.2177 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.60%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6089 mL 13.0443 mL 26.0885 mL 65.2214 mL
5 mM 0.5218 mL 2.6089 mL 5.2177 mL 13.0443 mL
10 mM 0.2609 mL 1.3044 mL 2.6089 mL 6.5221 mL
15 mM 0.1739 mL 0.8696 mL 1.7392 mL 4.3481 mL
20 mM 0.1304 mL 0.6522 mL 1.3044 mL 3.2611 mL
25 mM 0.1044 mL 0.5218 mL 1.0435 mL 2.6089 mL
30 mM 0.0870 mL 0.4348 mL 0.8696 mL 2.1740 mL
40 mM 0.0652 mL 0.3261 mL 0.6522 mL 1.6305 mL
50 mM 0.0522 mL 0.2609 mL 0.5218 mL 1.3044 mL
60 mM 0.0435 mL 0.2174 mL 0.4348 mL 1.0870 mL
80 mM 0.0326 mL 0.1631 mL 0.3261 mL 0.8153 mL
100 mM 0.0261 mL 0.1304 mL 0.2609 mL 0.6522 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Succinyladenosine
Cat. No.:
HY-113284
Quantity:
MCE Japan Authorized Agent: