SLC16A11 - solute carrier family 16 member 11 Gene

Also Known as MCT11; MCT 11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 162515

About SLC16A11

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,041,621-7,044,092 (from NCBI)

This gene has 4 transcripts (splice variants), 271 orthologues and 13 paralogues. Broad expression in kidney (RPKM 1.1), lung (RPKM 1.1) and 22 other tissues.

Summary

Enables pyruvate transmembrane transporter activity. Involved in lipid metabolic process. Located in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A11 Products (3)

mRNA Protein Name
NM_001370549.1 NP_001357478.1 monocarboxylate transporter 11 isoform 1
NM_001370553.1 NP_001357482.1 monocarboxylate transporter 11 isoform 2
NM_153357.3 NP_699188.2 monocarboxylate transporter 11 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28666119 GOA
enables pyruvate transmembrane transporter activity IDA
IDA: Inferred from direct assay
28666119 GOA
Biological Process GO Annotation Evidence References Source
involved in lipid metabolic process IDA
IDA: Inferred from direct assay
24390345 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
24390345 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
28666119 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC16A11 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (46 - 318)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 471 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 11

  • monocarboxylic acid transporter 11

SLC16A11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC16A11 Q8NCK7 BSG Homo sapiens P35613
Anti Tag CoIP
28666119
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13020 SLC16A11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC16A11 VGNC VGNC:34685
Canis familiaris SLC16A11 VGNC VGNC:46237
Rattus norvegicus SLC16A11 RGD RGD:1311125
Felis catus SLC16A11 VGNC VGNC:65205
Mus musculus SLC16A11 MGD MGI:2663709
Macaca mulatta SLC16A11 VGNC VGNC:77558
Others SLC16A11 NCBI