Kcnk1 - potassium channel, subfamily K, member 1 Gene

Also Known as TWIK-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16525

Summary

Enables inward rectifier Potassium Channel activity. Involved in potassium ion transmembrane transport. Located in endosome. Is integral component of plasma membrane. Part of inward rectifier Potassium Channel complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk1 Products (1)

mRNA Protein Name
NM_008430.2 NP_032456.2 potassium channel subfamily K member 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
24496152 MGI
enables inward rectifier potassium channel activity IDA
IDA: Inferred from direct assay
9013852 MGI
enables ligand-gated channel activity IDA
IDA: Inferred from direct assay
24496152 MGI
enables potassium channel activity IDA
IDA: Inferred from direct assay
15540117 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15540117 MGI
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
24496152 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
25406588 MGI
enables voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
25406588 MGI
Biological Process GO Annotation Evidence References Source
involved in chloride transmembrane transport IDA
IDA: Inferred from direct assay
24496152 MGI
involved in glutamate secretion IDA
IDA: Inferred from direct assay
24496152 MGI
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
9013852 MGI
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
15540117 MGI
part of inward rectifier potassium channel complex IDA
IDA: Inferred from direct assay
9013852 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24496152 MGI
located in plasma membrane IMP
IMP: Inferred from mutant phenotype
9013852 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily K member 1

  • inward rectifying potassium channel protein TWIK-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07152 KCNK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21612 Kcnk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28130 Kcnk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnk1 NCBI NCBI:3775