Ugcg - UDP-glucose ceramide glucosyltransferase Gene

Mus musculus

Also known as Ugcgl; Epcs21; GlcT-1

Gene ID: 22234 | Gene type: protein coding

About Ugcg

Chromosome 4: 59,189,257-59,222,833 forward strand.GRCm39:CM000997.3

This gene has 4 transcripts (splice variants), 212 orthologues and is associated with 13 phenotypes. Ubiquitous expression in CNS E18 (RPKM 2.2), whole brain E14.5 (RPKM 18.2) and 28 other tissues.

Summary

Enables ceramide glucosyltransferase activity. Involved in several processes, including cornified envelope assembly; glucosylceramide biosynthetic process; and skin development. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in several structures, including blastocyst; brain; early embryo; liver; and oocyte. Orthologous to human UGCG (UDP-glucose ceramide glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Ugcg Products(1)

mRNA	Protein	Name
NM_011673.3	NP_035803.1	ceramide glucosyltransferase

Ugcg Protein Structure

Glucosylceramide_synthase

0
100
200
300
394 a.a.

Protein Preferred Names

Protein Names

ceramide glucosyltransferase

GCS	UDP-glucose:N-acylsphingosine D-glucosyltransferase
ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 21	glucosylceramide synthase
glycosylceramide synthase

Related Agents

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-132596	Tivanisiran	Inhibitor	/	Phase 3
HY-148100	Emapticap pegol		/	Phase 2

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS15419	UGCG Human Pre-designed siRNA Set A	/	Unkown
HY-RS15420	Ugcg Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS15421	Ugcg Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ugcg	NCBI	NCBI:7357

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