CUL9 - cullin 9 Gene

Also Known as PARC; H7AP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23113

About CUL9

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,182,196-43,224,587 (from NCBI)

This gene has 18 transcripts (splice variants), 243 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 6.1), skin (RPKM 5.9) and 25 other tissues.

Summary

Predicted to enable several functions, including ATP binding activity; metal ion binding activity; and ubiquitin protein Ligase binding activity. Involved in microtubule Cytoskeleton organization; protein ubiquitination; and regulation of mitotic nuclear division. Located in cytosol. Part of cullin-RING ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

CUL9 Products (1)

mRNA Protein Name
NM_015089.4 NP_055904.1 cullin-9

CUL9 Protein Structure

Cul7

Cul7: Mouse development and cellular proliferation protein Cullin-7 (366 - 440)

ANAPC10

ANAPC10: Anaphase-promoting complex, subunit 10 (APC10) (1182 - 1300)

Cullin

Cullin: Cullin family (1415 - 1836)

IBR

IBR: IBR domain, a half RING-finger domain (2141 - 2203)

IBR

IBR: IBR domain, a half RING-finger domain (2231 - 2273)

  • 0
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  • 2000
  • 2400
  • 2517 a.a.
Protein Preferred Names Protein Names

cullin-9

  • CUL-9

CUL9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CUL9 Q8IWT3 TP53 Homo sapiens P04637
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Amelogenesis Imperfecta, Hypomaturation Type, Iia3

  • Amelogenesis Imperfecta Hypomaturation Type 2a3

  • AI2A3

  • Amelogenesis Imperfecta Hypomaturation Type Iia3

  • Amelogenesis Imperfecta, Type Iia3

  • Amelogenesis Imperfecta Type Iia3

  • Amelogenesis Imperfecta, Hypomaturation Type, 2a3
Three M Syndrome 1

  • 3-M Syndrome

  • Yakut Short Stature Syndrome

  • 3m Syndrome

  • Le Merrer Syndrome

  • Dolichospondylic Dysplasia

  • Gloomy Face Syndrome

  • Three M Syndrome

  • 3M1

  • 3m Syndrome 1

  • Miller-Mckusick-Malvaux Syndrome

  • 3-Msbn

  • Three-M Slender-Boned Nanism

  • Miller-Mckusick-Malvaux-Syndrome

  • 3-M Syndrome 1

  • 3m Syndrome-1

  • 3m Syndrome, Type 1

  • Dwarfism

  • Dwarfism Tall Vertebrae
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03366 CUL9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22134 Cul9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CUL9 VGNC VGNC:39735
Mus musculus CUL9 MGD MGI:1925559
Bos taurus CUL9 VGNC VGNC:27836
Felis catus CUL9 VGNC VGNC:61288
Macaca mulatta CUL9 VGNC VGNC:71416
Rattus norvegicus CUL9 RGD RGD:1562008
Others CUL9 NCBI