Aldob - aldolase, fructose-bisphosphate B Gene

Also Known as Aldo2; LIV10

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24190

Summary

Enables fructose-bisphosphate aldolase activity and phosphatidylcholine binding activity. Involved in several processes, including cellular response to Insulin stimulus; response to copper ion; and response to fructose. Located in several cellular components, including endoplasmic reticulum membrane; lysosome; and perinuclear region of cytoplasm. Used to study type 2 diabetes mellitus. Biomarker of liver benign neoplasm; peritonitis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B). [provided by Alliance of Genome Resources, Apr 2022]

Aldob Products (1)

mRNA Protein Name
NM_012496.2 NP_036628.2 fructose-bisphosphate aldolase B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fructose-bisphosphate aldolase activity IDA
IDA: Inferred from direct assay
9448062 RGD
enables phosphatidylcholine binding IPI
IPI: Inferred from physical interaction
9448062 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
9473304 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
8641049 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
2984252 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
2984252 RGD
involved in response to carbohydrate IEP
IEP: Inferred from expression pattern
6689021 RGD
involved in response to copper ion IEP
IEP: Inferred from expression pattern
11044632 RGD
involved in response to fructose IEP
IEP: Inferred from expression pattern
2984252 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
9473304 RGD
involved in response to interleukin-6 IEP
IEP: Inferred from expression pattern
7625825 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
9020521 RGD
involved in response to peptide hormone IDA
IDA: Inferred from direct assay
10775441 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
9886486 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12387752 RGD
involved in response to zinc ion IDA
IDA: Inferred from direct assay
12721403 RGD
Cellular Component GO Annotation Evidence References Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
10797566 RGD
located in rough endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
234468 RGD
located in smooth endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
234468 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fructose-bisphosphate aldolase B

  • Aldolase B, fructose-biphosphate

  • aldolase B, fructose-bisphosphate

  • liver-type aldolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS17969 Aldob Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00584 ALDOB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24440 Aldob Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldob NCBI NCBI:229