Cyp1a2 - cytochrome P450, family 1, subfamily a, polypeptide 2 Gene

Also Known as CYPD45; P-450d; RATCYPD45

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24297

Summary

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including cellular response to copper ion; response to estradiol; and response to lipopolysaccharide. Located in intracellular membrane-bounded organelle. Biomarker of mental depression. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (Cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp1a2 Products (1)

mRNA Protein Name
NM_012541.3 NP_036673.3 cytochrome P450 1A2
Protein Preferred Names Protein Names

cytochrome P450 1A2

  • CYPIA2

  • Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d)

  • P-448

  • P450-D

  • cholesterol 25-hydroxylase

  • cytochrome P-448

  • cytochrome P-450d

  • cytochrome P450, 1a2

  • cytochrome P450, subfamily I (aromatic compound-inducible), mem

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp1a2 NCBI NCBI:1544