Tor1aip1 - torsin 1A interacting protein 1 Gene

Also Known as Lap1b; Lap1c

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246314

Summary

Enables lamin binding activity. Predicted to be involved in nuclear membrane organization; positive regulation of ATPase activity; and protein localization to nucleus. Predicted to act upstream of or within protein localization to nuclear envelope. Located in nuclear envelope. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Y. Orthologous to human TOR1AIP1 (torsin 1A interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tor1aip1 Products (1)

mRNA Protein Name
NM_145092.2 NP_659560.2 torsin-1A-interacting protein 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lamin binding IDA
IDA: Inferred from direct assay
7721789 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17592128 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
7721789 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

torsin-1A-interacting protein 1

  • lamina-associated polypeptide 1B

  • lamina-associated polypeptide 1C

  • torsin A interacting protein 1

Tor1aip1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tor1aip1 Q5PQX1 Ppp1ca Rattus norvegicus P62138
Anti Bait CoIP
24116158
Intra
Tor1aip1 Q5PQX1 Ppp1cc Rattus norvegicus P63088
Anti Bait CoIP
24116158
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14904 TOR1AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tor1aip1 NCBI NCBI:26092