1. Gene
  2. Slc2a2 - solute carrier family 2 member 2 Gene

Slc2a2 - solute carrier family 2 member 2 Gene

Rattus norvegicus

Also known as GTT2; Glut2

Gene ID: 25351 | Gene type: protein coding

About Slc2a2

Primary_assembly 2: 111,611,774-111,639,933 forward strand.mRatBN7.2:CM026975.1

This gene has 3 transcripts (splice variants), 312 orthologues, 12 paralogues and is associated with 15 phenotypes. Biased expression in Liver (RPKM 1233.6) and Kidney (RPKM 253.5).

Summary

Enables D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and Insulin Receptor binding activity. Involved in several processes, including carbohydrate utilization; dehydroascorbic acid transport; and hexose transmembrane transport. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and brush border membrane. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to human SLC2A2 (solute carrier family 2 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a2 Products(1)

mRNA Protein Name
NM_012879.2 NP_037011.2 solute carrier family 2, facilitated glucose transporter member 2

Slc2a2 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (11 - 487)

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  • 522 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 2

GLUT-2

glucose transporter type 2, liver

solute carrier family 2 (facilitated glucose transporter), member 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a2 NCBI NCBI:6514