2. Gene
  3. Syt3 - synaptotagmin 3 Gene

Syt3 - synaptotagmin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as SIII

Gene ID: 25731 | Gene type: protein coding

About Syt3

Summary

Enables clathrin binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in positive regulation of vesicle fusion; regulation of calcium ion-dependent exocytosis; and response to calcium ion. Is integral component of synaptic membrane. Orthologous to human SYT3 (synaptotagmin 3). [provided by Alliance of Genome Resources, Apr 2022]

Syt3 Products(1)

mRNA Protein Name
NM_019122.1 NP_061995.1 synaptotagmin-3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SNARE binding IDA
IDA: Inferred from direct assay
12860971 RGD
enables calcium-dependent phospholipid binding IDA
IDA: Inferred from direct assay
7791877 RGD
enables clathrin binding IDA
IDA: Inferred from direct assay
7791877 RGD
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
12860971 RGD
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
12860971 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9830048 RGD
enables syntaxin binding IDA
IDA: Inferred from direct assay
7791877 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of vesicle fusion IDA
IDA: Inferred from direct assay
18508778 RGD
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
12860971 RGD
involved in response to calcium ion IDA
IDA: Inferred from direct assay
18508778 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in synaptic membrane EXP
EXP: Inferred from Experiment
10373432 RGD
is active in synaptic membrane IDA
IDA: Inferred from direct assay
10373432 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-3

synaptotagmin III

sytIII

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14115 SYT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syt3 NCBI NCBI:84258