SYT3 - synaptotagmin 3 Gene

Homo sapiens

Also known as SytIII

Gene ID: 84258 | Gene type: protein coding

About SYT3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:50,621,977-50,639,881 (from NCBI)

This gene has 6 transcripts (splice variants), 180 orthologues and 31 paralogues. Biased expression in brain (RPKM 3.3), testis (RPKM 0.5) and 3 other tissues.

Summary

Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Located in endosome. [provided by Alliance of Genome Resources, Apr 2022]

SYT3 Products(3)

mRNA	Protein	Name
NM_001160328.2	NP_001153800.1	synaptotagmin-3
NM_001160329.2	NP_001153801.1	synaptotagmin-3
NM_032298.3	NP_115674.1	synaptotagmin-3

SYT3 Protein Structure

0
100
200
300
400
500
590 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-3

synaptotagmin III

Related Diseases

Diseases

Alias

Deafness, Autosomal Recessive 9

Auditory Neuropathy, Autosomal Recessive, 1	Neurosensory Nonsyndromic Recessive Deafness 9
DFNB9	Nsrd9
Autosomal Recessive Nonsyndromic Deafness 9	Autosomal Recessive Deafness 9
Nrsd9	AUNB1
Nonsyndromic Auditory Neuropathy Autosomal Recessive	Nsran
Deafness, Autosomal Recessive, 9	Deafness Neurosensory Autosomal Recessive 9
Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 9	Non-Syndromic Recessive Hearing Loss 9
Deafness, Autosomal Recessive, Type 9	Auditory Neuropathy, Nonsyndromic Recessive

Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b

Lgmd2b	Lgmd3
Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency	Limb-Girdle Muscular Dystrophy Type 3
Muscular Dystrophy, Limb-Girdle, Type 2b

Autosomal Recessive Limb-Girdle Muscular Dystrophy

Muscular Dystrophy, Limb-Girdle, Autosomal Recessive

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14115	SYT3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SYT3	RGD	RGD:3805
Canis familiaris	SYT3	VGNC	VGNC:47046
Mus musculus	SYT3	MGD	MGI:99665
Felis catus	SYT3	VGNC	VGNC:65899
Bos taurus	SYT3	VGNC	VGNC:35542