2. Gene
  3. Psma6 - proteasome subunit alpha 6 Gene

Psma6 - proteasome subunit alpha 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IOTA

Gene ID: 26443 | Gene type: protein coding

About Psma6

Summary

Enables RNA binding activity. Predicted to be involved in positive regulation of NF-kappaB transcription factor activity and proteasomal protein catabolic process. Located in P-body and nuclear matrix. Part of Proteasome core complex. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PSMA6 (Proteasome 20S subunit alpha 6). [provided by Alliance of Genome Resources, Apr 2022]

Psma6 Products(2)

mRNA Protein Name
NM_001310583.1 NP_001297512.1 proteasome subunit alpha type-6 isoform 2
NM_011968.3 NP_036098.1 proteasome subunit alpha type-6 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IDA
IDA: Inferred from direct assay
10852819 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31915251 MGI
Cellular Component GO Annotation Evidence Reference Source
located in P-body IDA
IDA: Inferred from direct assay
22078707 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10852819 MGI
located in nuclear matrix IDA
IDA: Inferred from direct assay
10852819 MGI
part of proteasome core complex IDA
IDA: Inferred from direct assay
16857966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome subunit alpha type-6

macropain iota chain

multicatalytic endopeptidase complex iota chain

proteasome (prosome, macropain) subunit, alpha type 6

proteasome iota chain

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P11485 JR11-PEG3-HBED-CC-PSMA-03 / Unkown
HY-P11488 JR11-PEG3-DOTA-PSMA-03 Ligand / Unkown
HY-RS11296 PSMA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psma6 NCBI NCBI:5687