Psma6 - proteasome subunit alpha 6 Gene

Also Known as IOTA

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26443

Summary

Enables RNA binding activity. Predicted to be involved in positive regulation of NF-kappaB transcription factor activity and proteasomal protein catabolic process. Located in P-body and nuclear matrix. Part of Proteasome core complex. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PSMA6 (Proteasome 20S subunit alpha 6). [provided by Alliance of Genome Resources, Apr 2022]

Psma6 Products (2)

mRNA Protein Name
NM_001310583.1 NP_001297512.1 proteasome subunit alpha type-6 isoform 2
NM_011968.3 NP_036098.1 proteasome subunit alpha type-6 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
10852819 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31915251 MGI
Cellular Component GO Annotation Evidence References Source
located in P-body IDA
IDA: Inferred from direct assay
22078707 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10852819 MGI
located in nuclear matrix IDA
IDA: Inferred from direct assay
10852819 MGI
part of proteasome core complex IDA
IDA: Inferred from direct assay
16857966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome subunit alpha type-6

  • macropain iota chain

  • multicatalytic endopeptidase complex iota chain

  • proteasome (prosome, macropain) subunit, alpha type 6

  • proteasome iota chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11485 JR11-PEG3-HBED-CC-PSMA-03 / Unkown
HY-P11488 JR11-PEG3-DOTA-PSMA-03 Ligand / Unkown
HY-RS11296 PSMA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psma6 NCBI NCBI:5687