2. Gene
  3. Homer2 - homer scaffolding protein 2 Gene

Homer2 - homer scaffolding protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CPD; Vesl-2; 9330120H11Rik

Gene ID: 26557 | Gene type: protein coding

About Homer2

Summary

Enables actin binding activity and synaptic receptor adaptor activity. Involved in sensory perception of sound. Acts upstream of or within several processes, including behavioral response to cocaine; calcium-mediated signaling using intracellular calcium source; and chemical homeostasis within a tissue. Located in several cellular components, including apical part of cell; postsynaptic density; and stereocilium tip. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; cranial nerve; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to human HOMER2 (homer scaffold protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Homer2 Products(3)

mRNA Protein Name
NM_001164086.1 NP_001157558.1 homer protein homolog 2 isoform 2
NM_001164087.1 NP_001157559.1 homer protein homolog 2 isoform 3
NM_011983.2 NP_036113.1 homer protein homolog 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables actin binding IDA
IDA: Inferred from direct assay
10493740 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9808458 MGI
enables synaptic receptor adaptor activity IDA
IDA: Inferred from direct assay
10493740 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within behavioral response to cocaine IMP
IMP: Inferred from mutant phenotype
15294147 MGI
acts upstream of or within calcium-mediated signaling IMP
IMP: Inferred from mutant phenotype
12860966 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12860966 MGI
involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
25816005 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical part of cell IDA
IDA: Inferred from direct assay
12860966 MGI
located in cytoplasm IMP
IMP: Inferred from mutant phenotype
10493740 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24530450 MGI
is active in postsynaptic density IDA
IDA: Inferred from direct assay
24530450 MGI
located in stereocilium tip IDA
IDA: Inferred from direct assay
25816005 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homer protein homolog 2

VASP/Ena-related gene up-regulated during seizure and LTP 2

cupidin

homer homolog 2

homer, neuronal immediate early gene, 2

homer-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06284 HOMER2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Homer2 NCBI NCBI:9455