2. Gene
  3. Slc4a11 - solute carrier family 4, sodium bicarbonate transporter-like, member 11 Gene

Slc4a11 - solute carrier family 4, sodium bicarbonate transporter-like, member 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BTR1; NaBC1

Gene ID: 269356 | Gene type: protein coding

About Slc4a11

Summary

Predicted to enable ion transmembrane transporter activity; protein dimerization activity; and water transmembrane transporter activity. Involved in fluid transport; ion homeostasis; and regulation of mesenchymal stem cell differentiation. Located in basolateral plasma membrane. Is expressed in metanephros and vomeronasal organ. Used to study congenital hereditary endothelial dystrophy of cornea. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Orthologous to human SLC4A11 (solute carrier family 4 member 11). [provided by Alliance of Genome Resources, Apr 2022]

Slc4a11 Products(1)

mRNA Protein Name
NM_001081162.1 NP_001074631.1 solute carrier family 4 member 11
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in fluid transport IMP
IMP: Inferred from mutant phenotype
20185830 MGI
involved in monoatomic ion homeostasis IMP
IMP: Inferred from mutant phenotype
20185830 MGI
involved in regulation of mesenchymal stem cell differentiation IMP
IMP: Inferred from mutant phenotype
33247189 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
23813972 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 4 member 11

sodium bicarbonate transporter-like protein 11

bicarbonate transporter-related protein 1

sodium borate cotransporter 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-177554 KB05yne 99.97% Unkown
HY-RS13267 SLC4A11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-185414 KB05-Biotin / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc4a11 NCBI NCBI:83959