Map3k10 - mitogen-activated protein kinase kinase kinase 10 Gene

Also Known as MST; Mlk2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269881

Summary

Enables protein kinase activity and transcription corepressor activity. Acts upstream of or within negative regulation of transcription, DNA-templated and protein phosphorylation. Predicted to be located in cytoplasm. Is expressed in brown fat; heart; ovary; renal vasculature; and testis. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10). [provided by Alliance of Genome Resources, Apr 2022]

Map3k10 Products (1)

mRNA Protein Name
NM_001290528.1 NP_001277457.1 mitogen-activated protein kinase kinase kinase 10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15062575 MGI
enables protein kinase activity IDA
IDA: Inferred from direct assay
15062575 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
15062575 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15062575 MGI
acts upstream of or within protein phosphorylation IPI
IPI: Inferred from physical interaction
15062575 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 10

  • MKN28 derived nonreceptor_type

  • MKN28 kinase

  • mixed lineage kinase 2

  • serine/threonine kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175809 SRT6 Inhibitor / Unkown
HY-RS08047 MAP3K10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k10 NCBI NCBI:4294