2. Gene
  3. Lpcat2 - lysophosphatidylcholine acyltransferase 2 Gene

Lpcat2 - lysophosphatidylcholine acyltransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Aytl1; Aytl1a; lpafat1; lysoPAFAT; 1-AGPAT 11; A330042H22; lysoPAFAT/LPCAT2

Gene ID: 270084 | Gene type: protein coding

About Lpcat2

Summary

Enables 1-acylglycerophosphocholine O-acyltransferase activity and 1-alkylglycerophosphocholine O-acetyltransferase activity. Involved in membrane organization and platelet activating factor biosynthetic process. Located in Golgi stack; endoplasmic reticulum; and membrane. Orthologous to human LPCAT2 (lysophosphatidylcholine Acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Lpcat2 Products(3)

mRNA Protein Name
NM_001357374.1 NP_001344303.1 lysophosphatidylcholine acyltransferase 2 isoform b
NM_001357375.1 NP_001344304.1 lysophosphatidylcholine acyltransferase 2 isoform c
NM_173014.2 NP_766602.1 lysophosphatidylcholine acyltransferase 2 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 1-acylglycerophosphocholine O-acyltransferase activity IDA
IDA: Inferred from direct assay
17182612 MGI
enables 1-alkylglycerophosphocholine O-acetyltransferase activity IDA
IDA: Inferred from direct assay
17182612 MGI
Biological Process GO Annotation Evidence Reference Source
involved in membrane organization IDA
IDA: Inferred from direct assay
17182612 MGI
involved in platelet activating factor biosynthetic process IDA
IDA: Inferred from direct assay
17182612 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Golgi stack IDA
IDA: Inferred from direct assay
17182612 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
17182612 MGI
located in membrane IDA
IDA: Inferred from direct assay
18156367 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysophosphatidylcholine acyltransferase 2

1-AGP acyltransferase 11

1-acylglycerol-3-phosphate O-acyltransferase 11

1-acylglycerophosphocholine O-acyltransferase

1-alkenylglycerophosphocholine O-acyltransferase

1-alkylglycerophosphocholine O-acetyltransferase

LPC acyltransferase 2

acetyl-CoA

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112825 TSI-01 Inhibitor 98.52% Unkown
HY-RS07765 LPCAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpcat2 NCBI NCBI:54947