Lpcat2 - lysophosphatidylcholine acyltransferase 2 Gene

Also Known as Aytl1; Aytl1a; lpafat1; lysoPAFAT; 1-AGPAT 11; A330042H22; lysoPAFAT/LPCAT2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 270084

Summary

Enables 1-acylglycerophosphocholine O-acyltransferase activity and 1-alkylglycerophosphocholine O-acetyltransferase activity. Involved in membrane organization and platelet activating factor biosynthetic process. Located in Golgi stack; endoplasmic reticulum; and membrane. Orthologous to human LPCAT2 (lysophosphatidylcholine Acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Lpcat2 Products (3)

mRNA Protein Name
NM_001357374.1 NP_001344303.1 lysophosphatidylcholine acyltransferase 2 isoform b
NM_001357375.1 NP_001344304.1 lysophosphatidylcholine acyltransferase 2 isoform c
NM_173014.2 NP_766602.1 lysophosphatidylcholine acyltransferase 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-acylglycerophosphocholine O-acyltransferase activity IDA
IDA: Inferred from direct assay
17182612 MGI
enables 1-alkylglycerophosphocholine O-acetyltransferase activity IDA
IDA: Inferred from direct assay
17182612 MGI
Biological Process GO Annotation Evidence References Source
involved in membrane organization IDA
IDA: Inferred from direct assay
17182612 MGI
involved in platelet activating factor biosynthetic process IDA
IDA: Inferred from direct assay
17182612 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi stack IDA
IDA: Inferred from direct assay
17182612 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
17182612 MGI
located in membrane IDA
IDA: Inferred from direct assay
18156367 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysophosphatidylcholine acyltransferase 2

  • 1-AGP acyltransferase 11

  • 1-acylglycerol-3-phosphate O-acyltransferase 11

  • 1-acylglycerophosphocholine O-acyltransferase

  • 1-alkenylglycerophosphocholine O-acyltransferase

  • 1-alkylglycerophosphocholine O-acetyltransferase

  • LPC acyltransferase 2

  • acetyl-CoA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112825 TSI-01 Inhibitor 98.52% Unkown
HY-RS07765 LPCAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpcat2 NCBI NCBI:54947