Shc4 - SHC (Src homology 2 domain containing) family, member 4 Gene

Also Known as RaLP; Gm685; 6230417E10Rik; 9930029B02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 271849

Summary

Enables protein domain specific binding activity and receptor tyrosine kinase binding activity. Acts upstream of or within several processes, including apoptotic process; positive regulation of cell population proliferation; and stem cell differentiation. Predicted to be located in postsynaptic membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; heart; sensory organ; and skin. Orthologous to human SHC4 (SHC adaptor protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Shc4 Products (1)

mRNA Protein Name
NM_199022.3 NP_950187.1 SHC-transforming protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
17452444 MGI
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
17452444 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within apoptotic process IMP
IMP: Inferred from mutant phenotype
22948967 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
22948967 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22948967 MGI
acts upstream of or within stem cell differentiation IMP
IMP: Inferred from mutant phenotype
22948967 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SHC-transforming protein 4

  • SH2 domain protein C4

  • SHC-transforming protein D

  • mShcD

  • novel phosphotyrosine interaction domain (PTB/PID) and SH2 domains containing protein

  • rai-like protein RaLP

  • src homology 2 domain-containing-transforming protein C4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-161464 Chlopynostat 98.36% Unkown
HY-RS12859 SHC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shc4 NCBI NCBI:399694