Dnajb9 - DnaJ heat shock protein family (Hsp40) member B9 Gene

Mus musculus

Also known as Mdg1; mDj7; ERdj4

Gene ID: 27362 | Gene type: protein coding

About Dnajb9

Summary

Enables HSP70 protein binding activity and chaperone binding activity. Involved in B cell differentiation; positive regulation of immunoglobulin production; and ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum lumen. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human DNAJB9 (DnaJ heat shock protein family (HSP40) member B9). [provided by Alliance of Genome Resources, Apr 2022]

Dnajb9 Products(1)

mRNA	Protein	Name
NM_013760.4	NP_038788.2	dnaJ homolog subfamily B member 9 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables Hsp70 protein binding	IPI IPI: Inferred from physical interaction	11836248	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22267725	MGI
enables protein-folding chaperone binding	IDA IDA: Inferred from direct assay	11836248	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in B cell differentiation	IMP IMP: Inferred from mutant phenotype	25222125	MGI
involved in ERAD pathway	IDA IDA: Inferred from direct assay	22267725	MGI
involved in positive regulation of immunoglobulin production	IMP IMP: Inferred from mutant phenotype	25222125	MGI
involved in response to endoplasmic reticulum stress	IDA IDA: Inferred from direct assay	11836248	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	11836248	MGI
located in endoplasmic reticulum lumen	IDA IDA: Inferred from direct assay	22267725	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dnaJ homolog subfamily B member 9

DNA j protein b9	DnaJ (Hsp40) homolog, subfamily B, member 9
ER-resident protein ERdj4	endoplasmic reticulum DNA J domain-containing protein 4
microvascular endothelial differentiation gene 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03871	DNAJB9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dnajb9	NCBI	NCBI:4189

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