Srr - serine racemase Gene

Also Known as Srs; Rgsc34; M100034

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27364

Summary

Enables several functions, including amino-acid racemase activity; anion binding activity; and identical protein binding activity. Acts upstream of or within D-serine biosynthetic process and L-serine metabolic process. Predicted to be located in apical part of cell; neuronal cell body; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in facial bone primordium and nervous system. Used to study schizophrenia. Orthologous to human SRR (serine racemase). [provided by Alliance of Genome Resources, Apr 2022]

Srr Products (5)

mRNA Protein Name
NM_001163311.2 NP_001156783.1 serine racemase isoform 1
NM_001362742.1 NP_001349671.1 serine racemase isoform 2
NM_001362743.1 NP_001349672.1 serine racemase isoform 3
NM_001362744.1 NP_001349673.1 serine racemase isoform 4
NM_013761.5 NP_038789.1 serine racemase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
17293453 MGI
enables calcium ion binding IDA
IDA: Inferred from direct assay
12021263 MGI
enables glycine binding IDA
IDA: Inferred from direct assay
15710237 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
12021263 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12021263 MGI
enables pyridoxal phosphate binding IMP
IMP: Inferred from mutant phenotype
10557334 MGI
enables serine racemase activity IDA
IDA: Inferred from direct assay
10557334 MGI
enables threonine racemase activity IDA
IDA: Inferred from direct assay
15536068 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within D-serine biosynthetic process IDA
IDA: Inferred from direct assay
10557334 MGI
acts upstream of or within L-serine metabolic process IDA
IDA: Inferred from direct assay
10557334 MGI
acts upstream of or within serine family amino acid metabolic process IDA
IDA: Inferred from direct assay
15536068 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine racemase

  • D-serine ammonia-lyase

  • D-serine dehydratase

  • L-serine ammonia-lyase

  • L-serine dehydratase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W115558 L-Serine-O-sulfate potassium Inhibitor / Unkown
HY-RS13784 SRR Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srr NCBI NCBI:63826