SRR - serine racemase Gene

Homo sapiens

Also known as ILV1; ISO1

Gene ID: 63826 | Gene type: protein coding

About SRR

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,303,378-2,325,264 (from NCBI)

This gene has 8 transcripts (splice variants), 121 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 6.5), testis (RPKM 6.3) and 25 other tissues.

Summary

Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]

SRR Products(2)

mRNA	Protein	Name
NM_001304803.1	NP_001291732.1	serine racemase isoform b
NM_021947.3	NP_068766.1	serine racemase isoform a

SRR Protein Structure

PALP

0
100
200
300
340 a.a.

Protein Preferred Names

Protein Names

serine racemase

D-serine ammonia-lyase

Related Diseases

Diseases

Alias

Immunodeficiency 24

Severe Combined Immunodeficiency Due To Ctps1 Deficiency	IMD24
Scid Due To Ctps1 Deficiency	Immunodeficiency, Type 24

Serine Deficiency

Glanders

Farcy Pipes	Infection Due To Pseudomonas Mallei
Burkholderia Mallei	Burkholderia Mallei Infection
Equina	Equine Glanders
Farcy	Farcy Buds
Farcy Cords	Infection Due To Actinobacillus Mallei
Infection Due To Malleomyces Mallei	Maliasmus
Malleus	Farce
Actinobacillosis	Actinobacillus Infection

Subacute Bacterial Endocarditis

Endocarditis Lenta	Sbe - Subacute Bacterial Endocarditis
Subacute Endocarditis, Lenta	Endocarditis, Subacute Bacterial

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Syndromic X-Linked Intellectual Disability Snyder Type

Snyder-Robinson Syndrome	Mental Retardation, X-Linked, Snyder-Robinson Type
Spermine Synthase Deficiency	Srs
Snyder-Robinson Mental Retardation Syndrome	X-Linked Intellectual Disability Snyder-Robinson Type
Mental Retardation, X-Linked, Syndromic, Snyder-Robinson Type	Snyder-Robinson X-Linked Mental Retardation Syndrome

Psychotic Disorder

Psychotic Disorders	Mental Or Behavioural Disorder
Psychotic	Mental Disorders

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13784	SRR Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SRR	RGD	RGD:735094
Felis catus	SRR	VGNC	VGNC:65689
Bos taurus	SRR	VGNC	VGNC:35292
Mus musculus	SRR	MGD	MGI:1351636